Results 51 to 60 of about 4,610,729 (257)

Decreased MiR-17 in glioma cells increased cell viability and migration by increasing the expression of Cyclin D1, p-Akt and Akt. [PDF]

PLoS ONE, 2018
The activating mutations of micro RNA (miR)-17 have been revealed in tumors such as human non-Hodgkin's lymphoma and T cell leukemia. However, it is unclear about the role of miR-17 in glioma cells.
Guangwei Sun, Guozhong SiMa, Chunhui Wu, Yongzhong Fan, Yong Tan, Zhong Wang, Gang Cheng, Jie Li   +7 more
doaj   +1 more source

Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells [PDF]

Neuroectoderm-derived tumors characteristically express gangliosides such as GD3 and GD2. Many studies have reported that gangliosides GD3/GD2 enhance malignant phenotypes of cancers.
Kambe, Mariko, Ohkawa, Yuki, Furukawa, Keiko, Mizutani, Momoka, Furukawa, Koichi, Hashimoto, Noboru, Kawamoto, Yoshiyuki, Tajima, Orie, Hasnat, Mohammad Abul, Bhuiyan, Robiul H., Yesmin, Farhana, Kaneko, Kei, Tsuchida, Akiko, Ohmi, Yuhsuke   +13 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Modulação do sistema glutamatérgico por cisplatina em células de glioma humano e astrócitos corticais de ratos [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Neurociências, Florianópolis, 2013.Gliomas malignos constituem um grupo heterogêneo de tumores, com origem em precursores ...
Oliveira, Karen Andrinéia de
core  

Induction of neural differentiation in rat C6 glioma cells with taxol

, 2017
Background: Glioblastoma is a common and aggressive type of primary brain tumor. Several anticancer drugs affect GBM (glioblastoma multiforme) cells on cell growth and morphology. Taxol is one of the widely used antineoplastic drugs against many types of
盧國賢;錢宗良, Chao, Chuan-Chuan;Kan, Daphne;Lo, Ta-Hsuan;Lu, Kuo-Shyan;Chien, Chung-Liang   +1 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

RETRACTED: Marker-independent identification of glioma-initiating cells [PDF]

, 2010
Tumor-initiating cells with stem cell properties are believed to sustain the growth of gliomas, but proposed markers such as CD133 cannot be used to identify these cells with sufficient specificity.
Rolf Gruetter, Marie-France Hamou, Hamou, Marie-France, Ivan Radovanovic, Dietrich, Pierre-Yves, de Tribolet, N., Hegi, Monika E., Dietrich, P.Y., Monika E Hegi, Marino, D., Cudalbu, C., Hamou, M.F., Hegi, M.E., Hegi, M. E., Clement, Virginie, Radovanovic, I., Marino, Denis, Vladimir Mlynarik, Cudalbu, Cristina, Gruetter, R., Mlynarik, Vladimir, Cristina Cudalbu, Cudalbu, Cristina Ramona, de Tribolet, Nicolas, Clément, V., Radovanovic, Ivan, Virginie Clément, Mlynarik, V., Pierre-Yves Dietrich, Gruetter, Rolf, Denis Marino, Nicolas de Tribolet   +31 more
core   +2 more sources

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Lipid vesicles containing transferrin receptor binding peptide TfR-T12 and octa-arginine conjugate stearyl-R8 efficiently treat brain glioma along with glioma stem cells

Scientific Reports, 2017
Surgery and radiotherapy cannot fully remove brain glioma; thus, chemotherapy continues to play an important role in treatment of this illness. However, because of the restriction of the blood-brain barrier (BBB) and the regeneration of glioma stem cells,
Li-Min Mu, Ying-Zi Bu, Lei Liu, Hong-Jun Xie, Rui-Jun Ju, Jia-Shuan Wu, Fan Zeng, Yao Zhao, Jing-Ying Zhang, Wan-Liang Lu   +9 more
doaj   +1 more source

MiR-9 promotes tumorigenesis and angiogenesis and is activated by MYC and OCT4 in human glioma

Journal of Experimental & Clinical Cancer Research, 2019
Background Glioma, characterized by its undesirable prognosis and poor survival rate, is a serious threat to human health and lives. MicroRNA-9 (miR-9) is implicated in the regulation of multiple tumors, while the mechanisms underlying its aberrant ...
Xu Chen, Fan Yang, Tianze Zhang, Wei Wang, Wenjin Xi, Yufang Li, Dan Zhang, Yi Huo, Jianning Zhang, Angang Yang, Tao Wang   +10 more
doaj   +1 more source