Results 81 to 90 of about 4,610,729 (257)

Arsenic trioxide induces apoptosis and the formation of reactive oxygen species in rat glioma cells

Cellular & Molecular Biology Letters, 2018
Background Arsenic trioxide (As2O3) has a dramatic therapeutic effect on acute promyelocytic leukemia (APL) patients. It can also cause apoptosis in various tumor cells. This study investigated whether As2O3 has an antitumor effect on glioma and explored
Yuanyuan Sun, Chen Wang, Ligang Wang, Zhibo Dai, Kongbin Yang   +4 more
doaj   +1 more source

Comparação entre sistemas de degradação de peróxidos em fatias de hipocampo de ratos, glioma de ratos (C6) e neuroblastoma de camundongos (N2a) [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2010Estudo comparativo das atividades das enzimas antioxidantes catalase, glutationa peroxidase e ...
Mitozo, Péricles Arruda
core  

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Effect of PPARα Ligand on TNFα -Dependent Expression of EGF Receptor in Human Glioma Cell Line

, 2002
2002-12In glioma cells, tumor necrosis factor alpha (TNFα) was reported to increase the number of epidermal growth factor receptor (EGFR) that mediates EGF-dependent cell proliferation.
KAMBE, Fukushi, KATO, Mihoko, NAGAYA, Takashi, SAITO, Kiyoshi, YOSHIDA, Jun, SEO, Hisao, WAKABAYASHI, Kenichi   +6 more
core   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

The primary study on the application of gelatum invasive model as an invasiveness assay for glioma cells in vitro

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To investigate the feasibility of applying gelatum invasive model as an invasiveness assay for human glioma cells in vitro, observe the differences of invasiveness between adherently cultured differentiated human glioma cells and human glioma ...
Rui⁃fan XIE, Suo⁃jun ZHANG, Bao⁃cheng GAO, Feng WAN, Ting LEI   +4 more
doaj  

Fusion of glioma-associated mesenchymal stem/stromal cells with glioma cells promotes macrophage recruitment and M2 polarization via m6A modification of CSF1

Cell Death and Disease
Malignant glioma is the most common primary malignant tumor of the brain in adults, with glioblastoma (GBM) being the most aggressive subtype. Mesenchymal stem/stromal cells (MSCs) have been shown to fuse with tumor cells in various cancers including ...
Zhen Liu, Sujie Gu, Zesheng Peng, Yihao Wang, Hui Li, Xiaoqing Zeng, Haofei Wang, Peng Lv, Yuyi Wu, Yan Zhou, Yanbin Zhang, Xiaobing Jiang, Peng Fu   +12 more
doaj   +1 more source

Electrochemical Pathways for Nitrate Conversion to Ammonia: From Environmental Challenges to Ammonia Economy

Advanced Functional Materials, EarlyView.
This perspective presents recent advances in electrocatalytic nitrate reduction, focusing on reaction mechanisms, catalyst design, and electrolyzer configurations. Key challenges in selectivity, stability, and practical wastewater treatment are highlighted, while future directions for advancing sustainable ammonia synthesis and nitrate remediation are ...
Xintong Li, Yunpeng Zuo, Xiaoran Zhang, Jieqiong Shan, Kenneth Mei Yee Leung, Bin Liu, Peter Strasser, Adrian Fisher, Zonglong Zhu, Xin Wang   +9 more
wiley   +1 more source

The functional curcumin liposomes induce apoptosis in C6 glioblastoma cells and C6 glioblastoma stem cells in vitro and in animals

International Journal of Nanomedicine, 2017
Yahua Wang, Xue Ying, Haolun Xu, Helu Yan, Xia Li, Hui Tang Key Laboratory of Xinjiang Phytomedicine Resources and Modernization of TCM, School of Pharmaceutical Sciences, Shihezi University, Shihezi, Xinjiang, People’s Republic of China Abstract:
Wang YH, Ying X, Xu HL, Yan HL, Li X, Tang H   +5 more
doaj  

The role of NOTCH2 gene in human malignant glial brain tumours [PDF]

, 2008
Background: Glioblastoma multiforme (GBM), astrocytoma (A) and oligodendroglioma (OG) are the neoplasms of the glial lineage in the Central Nervous System (CNS).
Sivasankaran, Balasubramanian
core   +1 more source