Results 161 to 170 of about 79,800 (306)

The interacting etiologies of hippocampal sclerosis in epilepsy: A scoping review

open access: yesEpilepsia, EarlyView.
Abstract According to the International League Against Epilepsy classification, mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE‐HS) is considered an epilepsy syndrome. Several etiologies may precede HS, but there is little overview in the literature about these etiologies.
Boris Deleu   +2 more
wiley   +1 more source

Astrogliosis in the GFAP-CreERT2:Rosa26iDTR Mouse Model Does Not Exacerbate Retinal Microglia Activation or Müller Cell Gliosis under Hypoxic Conditions [PDF]

open access: gold
Colin Rorex   +7 more
openalex   +1 more source

A 17‐year‐old male with chronic epilepsy status post remote functional hemispherectomy

open access: yes
Brain Pathology, EarlyView.
Claire Voyles   +3 more
wiley   +1 more source

C1q neutralization during epileptogenesis attenuates complement‐mediated synaptic elimination and epileptiform activity

open access: yesEpilepsia, EarlyView.
Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong   +5 more
wiley   +1 more source

Olig2‐specific loss‐of‐function Slc35a2 results in hypomyelination and spontaneous seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective Malformations of cortical development represent major causes of drug‐resistant epilepsy, with mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy recognized as a distinct pathological entity. Pathogenic X‐linked SLC35A2, encoding the uridine diphosphate–galactose transporter, has been implicated ...
Tiffany M. Bartel   +6 more
wiley   +1 more source

Extracellular vesicle proteomics identifies novel blood biomarkers for the early diagnosis of status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to identify novel blood‐based biomarkers associated with the early diagnosis of status epilepticus (SE) by exploring proteomic alterations in plasma extracellular vesicles (EVs). Methods We conducted an observational and prospective study in a two‐phase design: a discovery proteomic analysis of plasma EVs ...
Estevo Santamarina   +11 more
wiley   +1 more source

WONOEP XVII appraisal: The immunopathogenesis of epilepsy

open access: yesEpilepsia, EarlyView.
Abstract There is a wealth of data indicating that the immune system plays an important role in seizure disorders. This includes autoimmune encephalitis, in which an immune response directed against neuronal antigens results in brain inflammation and subsequent seizure activity, as well as autoimmune‐associated epilepsy and neuroinflammatory changes ...
Nihan Çarçak   +12 more
wiley   +1 more source

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