Results 91 to 100 of about 4,429,182 (354)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Analysis of Stochastic Predator-Prey Model with Disease in the Prey and Holling Type II Functional Response

Advances in Mathematical Physics, 2020
A stochastic predator-prey model with disease in the prey and Holling type II functional response is proposed and its dynamics is analyzed. We discuss the boundedness of the dynamical system and find all feasible equilibrium solutions. For the stochastic
C. Gokila, M. Sambath, K. Balachandran, Yong-Ki Ma   +3 more
doaj   +1 more source

Global boundedness in a quasilinear fully parabolic chemotaxis system with indirect signal production

, 2017
In this paper we develop a new and convenient technique, with fractional Gagliardo-Nirenberg type inequalities inter alia involved, to treat the quasilinear fully parabolic chemotaxis system with indirect signal production: \begin{document}$ u_t = \nabla\
Mengyao Ding, Wei Wang
semanticscholar   +1 more source

Global boundedness of multilinear Fourier integral operators

, 2019
We establish global regularity of multilinear Fourier integral operators that are associated to nonlinear wave equations on product of $L^p$ spaces by proving endpoint boundedness on suitable products spaces containing combinations of the local Hardy space, the local BMO and the $L^2$ spaces.
Rodríguez-López, Salvador, Rule, David, Staubach, Wolfgang   +2 more
openaire   +3 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Existence of global solutions for a system of reaction-diffusion equations with exponential nonlinearity

Electronic Journal of Qualitative Theory of Differential Equations, 2009
We consider the question of global existence and uniform boundedness of nonnegative solutions of a system of reaction-diffusion equations with exponential nonlinearity using Lyapunov function techniques.
Elhachemi Daddiouaissa
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Global boundedness in a two-dimensional chemotaxis system with nonlinear diffusion and singular sensitivity

Advances in Nonlinear Analysis
In this study, we investigate the two-dimensional chemotaxis system with nonlinear diffusion and singular sensitivity: ut=∇⋅(uθ−1∇u)−χ∇⋅uv∇v,x∈Ω,t>0,vt=Δv−v+u+g(x,t),x∈Ω,t>0,(∗)\left\{\begin{array}{ll}{u}_{t}=\nabla \cdot \left({u}^{\theta -1}\nabla u ...
Ren Guoqiang, Zhou Xing
doaj   +1 more source

Mathematical analysis of toxin-phytoplankton-fish model with self-diffusion and cross-diffusion

Biomath, 2019
In this paper  we propose a nonlinear reaction-diffusion system  describing the interaction between toxin-producing phytoplankton and fish population. We analyze the effect of self- and cross-diffusion on the dynamics of the system.
Hamidou Ouedraogo, Wendkouni Ouedraogo, Boureima Sangaré   +2 more
doaj   +1 more source

Global Existence and Boundedness of the Solution for a Blood Oxygenation Model

Journal of Mathematical Analysis and Applications, 1994
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openaire   +3 more sources