Results 151 to 160 of about 6,655,877 (292)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Congo Basin Carbon Cycle Responses to Global Change. [PDF]

Glob Chang Biol
Worden S, Fu R, Bloom AA, Bauters M, Verbeeck H, Fatoyinbo T, Hubau W, Koutika LS, Kengdo SK, Maes SL, Medjibe V, Russo NJ, Saatchi S, Sagang LB, Smith TB, Sonwa DJ, Boeckx P, Ordway EM.   +17 more
europepmc   +1 more source

Observing Global Change in the Tropics [PDF]

, 2008
Wallace, Douglas W.R.
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Experimental Evidence for the Desynchronization of Ecosystem Dynamics by Global Change. [PDF]

Ecol Lett
Vagnon C, Chevalier M, Boulêtreau S, Bruel R, Guillon S, Holtgrieve G, Jackson M, Olden JD, Marin V, Millot A, Thebault E, Tedesco PA, Cucherousset J.   +12 more
europepmc   +1 more source

A Managerial Perspective on the Porter Hypothesis -The Case of CO2 Emissions [PDF]

Over the past decade, the debate on climate change has dramatically shifted. The strong evidence presented by the scientific community through the Intergovernmental Panel on Climate Change (IPCC) process established by the United Nations Environment ...
Diane-Laure Arjaliès, Jean-Pierre Ponssard   +1 more
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Global change factors differ in effect when acting alone and in a multi-factor background. [PDF]

Nat Commun
Rongstock R, Li H, Lehmann A, Wulf A, Rillig MC.   +4 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Global change

Geocarto International, 1987
T.F. Malone, J.G. Roederer, Kamlesh Lulla   +2 more
openaire   +2 more sources