Results 61 to 70 of about 4,277,769 (311)

全球教育的重要主題及其課程設計On Key Themes of Global Education and Their

open access: yesJournal of Curriculum Studies, 2012
有鑑於全球化的趨勢與衝擊愈來愈明顯,各國紛紛重視國際或全球教育的改革,尤其希望透過課程與教學的調整,培育具備國際觀、全球行動與競爭力的人才。本研究旨在探討全球教育課程的重要主題,並分析我國在國際教育課程設計上的現況與重點。首先,分析全球教育課程的內涵,繼之彙整英國與澳洲的課程設計實例,並進而探討全球教育課程設計的三類模式及其重要主題,包括第一類是透過五大類主題來彰顯全球教育內涵;第二類是透過全球性議題來建立全球公民素養;第三類則是透過合作專案學習來擴展國際視野 ...
林永豐 Yung-Feng Lin
doaj   +1 more source

NH International Seminar, Spring 2017: Migrations, Labor, and Natural Resources [PDF]

open access: yes, 2017
Nicole ConstableProfessor of Anthropology, University of PittsburghFebruary 7, 2017 Precarious Labor Migrations in Asia: An Anthropologist\u27s Perspective Mary MaloneAssociate Professor of Political Science, UNHMarch 21, 2017 Leaving the Devil You Know:
Center for International Education and Global Engagement
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Refugee Students Arrive at a School: What Happens Next?

open access: yesGlobal Education Review, 2018
As refugee children join classrooms across the world, schools have the opportunity to expand the global education of all students. Students, teachers, administrators, and families may partner together to form supportive environments.
Keri-Anne Croce
doaj  

Investigating Student Use of Technology for Engaged Citizenship in A Global Age

open access: yesEducation Sciences, 2012
This study undertook a five month qualitative investigation into technology use amongst twelve high school social studies students in two different sites in the Midwestern United States.
Brad M. Maguth
doaj   +1 more source

NH International Seminar, Spring 2016: Identity, Marginality & Community [PDF]

open access: yes, 2016
NHIS Spring 2016 - Identity, Marginality & Community Thursday, February 11, 2:10 – 3:30 pm, MUB Theater IIMarla Brettschneider, UNH Department of Women\u27s Studies and Political Science The Jewish Phenomenon in Sub-Saharan Africa Wednesday, March 2, 4 ...
Center for International Education and Global Engagement
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Global Health Education [PDF]

open access: yesSocial Work Research, 2016
Williams, James Herbert   +1 more
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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