Results 71 to 80 of about 11,103,208 (288)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

IMPACT OF GLOBAL FOOD SECURITY INDEX ADJUSTMENTS IN THE CONTEXT OF MAJOR INTERNATIONAL CHALLENGES [PDF]

Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development
Food security relies on interconnected social, economic, and biophysical systems to meet human nutritional requirements. Addressing risks is crucial for building resilience in food systems and ensuring long-term food security.
Eduard BOGHIŢĂ, Ştefan VIZITEU, Dan DONOSĂ   +2 more
doaj  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Emboldening food security for global sustainability yoking artificial intelligence

Discover Food
Food security is a fundamental global concern, where severe consequences may lead towards hunger and malnutrition. To intricate novel paradigm-shifting tactics correlating artificial intelligence and agriculture, the primary focus should rely on the ...
Gull-e-laala Khan, Gulshan Irshad, Raina Ijaz, Sabah Javaid, Noor Tahir, Sajid Mehmood   +5 more
doaj   +1 more source

Global Climatic Changes and Risks to Food Security a Narrative Review

Pakistan Armed Forces Medical Journal
A narrative review was conducted investigate the association of global climatic changes on food security, leading to malnutrition among women and children posed by environmental risks, using well-regarded databases such as Google Scholar, Pub Med, and ...
Nida Shoaib, Syeda Tabeena Ali, Sameera Ali Rizvi, Manesha Juriasinghani, Niaz Ahmed   +4 more
doaj   +1 more source

THE ECONOMIC PAMPHLETEER: Running Out of Land for Food

Journal of Agriculture, Food Systems, and Community Development, 2016
First paragraph: The challenge of preserving enough farmland for food production will be a defining challenge for the 21st century. Lester Brown, icon of the Worldwatch Institute, identifies food scarcity as "the weak link" of modern society (Brown, 2012)
John Ikerd
doaj   +1 more source

2011 Global food policy report

The year 2011 highlighted ongoing challenges to global food security, from food price volatility, extreme weather shocks, and famine to unrest and conflicts.
International Food Policy Research Institute
core   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Climate and carbon policy pathways for sustainable food systems

Environmental and Sustainability Indicators
Context & background: The global food system significantly contributes to climate change through carbon emissions. This article examines how policy interventions influence food affordability and supply, with a particular focus on climate change and ...
Zafar Said, Pethurajan Vigneshwaran, Saboor Shaik, Abdur Rauf, Zubair Ahmad   +4 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source