Results 61 to 70 of about 286,749 (305)

Fast multi-swarm optimization for dynamic optimization problems [PDF]

open access: yes, 2008
This article is posted here with permission of IEEE - Copyright @ 2008 IEEEIn the real world, many applications are non-stationary optimization problems. This requires that the optimization algorithms need to not only find the global optimal solution but
Yang, S   +5 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Filled Function Method Dominated by Filter for Nonlinearly Global Optimization

open access: yesJournal of Applied Mathematics, 2015
This work presents a filled function method based on the filter technique for global optimization. Filled function method is one of the effective methods for nonlinear global optimization, since it can effectively find a better minimizer.
Wei Wang, Xiaoshan Zhang, Min Li
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

GENERALIZED INVERSE INTERVAL METHOD OF GLOBAL CONSTRAINED OPTIMIZATION

open access: yesНаучный вестник МГТУ ГА, 2016
The algorithmic and program software of inverse interval method for global constrained optimization are considered. The solution of model examples and the proof of the theorems of the algorithm’s convergence are presented.
A. V. Panteleyev, V. N. Panovskiy
doaj  

Two-Phase Generalized Reduced Gradient Method for Constrained Global Optimization

open access: yesJournal of Applied Mathematics, 2010
The random perturbation of generalized reduced gradient method for optimization under nonlinear differentiable constraints is proposed. Generally speaking, a particular iteration of this method proceeds in two phases.
Abdelkrim El Mouatasim
doaj   +1 more source

A Stochastic Smoothing Method for Nonsmooth Global Optimization [PDF]

open access: yesCybernetics and Computer Technologies, 2020
The paper presents the results of testing the stochastic smoothing method for global optimization of a multiextremal function in a convex feasible subset of Euclidean space. Preliminarily, the objective function is extended outside the admissible region so that its global minimum does not change, and it becomes coercive.
openaire   +3 more sources

A New Hybrid Classical-quantum Algorithm For Continuous Global Optimization Problems

open access: yes, 2015
Grover’s algorithm can be employed in global optimization methods providing, in some cases, a quadratic speedup over classical algorithms. This paper describes a new method for continuous global optimization problems that uses a classical algorithm for ...
Lavor C., Lara P.C.S., Portugal R.
core   +1 more source

Optimization using surrogate models and partially converged computational fluid dynamics simulations [PDF]

open access: yes, 2006
Efficient methods for global aerodynamic optimization using computational fluid dynamics simulations should aim to reduce both the time taken to evaluate design concepts and the number of evaluations needed for optimization.
Alexander I.J. Forrester   +5 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy