Results 81 to 90 of about 286,749 (305)

Convergence analysis of an Inexact Infeasible Interior Point method for Semidefinite Programming [PDF]

, 2004
In this paper we present an extension to SDP of the well known infeasible Interior Point method for linear programming of Kojima,Megiddo and Mizuno (A primal-dual infeasible-interior-point algorithm for Linear Programming, Math. Progr., 1993).
Pieraccini, Sandra, Bellavia, S
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

基于同伦优化设计的机械零件可靠性优化设计

Jixie chuandong, 2008
Generally, action of constraints exists in reliability optimization design of mechanical parts. Usually, general optimum methods are adopted in reliability optimization design, so the local solution is obtained.
车晓毅, 罗佑新, 徐静蓉, 汪超, 何哲明   +4 more
doaj  

Global optimality conditions and optimization methods for polynomial programming problems

, 2015
This paper is concerned with the general polynomial programming problem with box constraints, including global optimality conditions and optimization methods.
Wu, Zhiyou, Ugon, Julien, Tian, Jing
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Optimization with missing data

, 2006
Engineering optimization relies routinely on deterministic computer based design evaluations, typically comprising geometry creation, mesh generation and numerical simulation.
Sobester, Andras, Keane, Andy J., Forrester, Alexander I.J.   +2 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Global Synthesis Method for the Optimization of Multifeed EBG Antennas

International Journal of Antennas and Propagation, 2008
This paper presents a novel technique for synthesizing a given radiation pattern from an EBG antenna with an array feed. The method determines the optimum sets of input waves and input impedances for the feed ports in order to perform simultaneously the ...
Julien Drouet, Marc Thevenot, Régis Chantalat, Cyrille Menudier, Majed Koubeissi, Thierry Monédière, Bernard Jecko   +6 more
doaj   +1 more source

Multi-objective optimization of grillages applying the genetic algorithm / Daugiakriteris sijynų optimizavimas genetiniais algoritmais

Mokslas: Lietuvos Ateitis, 2012
The article analyzes the optimization of grillage-type foundations seeking for the least possible reactive forces in the poles for a given number of poles and for the least possible bending moments of absolute values in the connecting beams of the ...
Darius Mačiūnas, Rimantas Belevičius, Juozas Kaunas   +2 more
doaj   +1 more source