Results 101 to 110 of about 2,317,544 (334)
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Frontiers in Veterinary Science, 2019 Vibrio aestuarianus is a bacterium related to mortality outbreaks in Pacific oysters, Crassostrea gigas, in France, Ireland, and Scotland since 2011. Knowledge about its transmission dynamics is still lacking, impairing guidance to prevent and control ...
Coralie Lupo +5 more
doaj +1 more source
Overview of global scale research Doppler lidar activities [PDF]
Efforts in support of a global backscatter mission are reviewed briefly. Lidar system sensitivity was calibrated by means of ground-based tests. The analysis of ground-based data and planning of a global backscatter mission were conducted.
Fitzjarrald, D. E.
core +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Buildings, 2015 Green roofs improve building energy performance and constitute an alternative to sustainable buildings. A green roof model is dynamically coupled with a building thermal model to assess its energy performance that takes into account the indoor air ...
Hery Tiana Rakotondramiarana +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Global Sensitivity Analysis of Poroelastic Soil Parameters
Poromechanics VI, 2017 In this proposal, we present a global sensitivity analysis method applied to the study of wave propagation occurring in a poroelastic material [Saltelli et al, 2008]. The global aim is to get relevant information in the investigation of the most influential poroelastic parameters.
Mesgouez, Arnaud +2 more
openaire +2 more sources
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
The primary objective is to determine the scope and interactions of the global water cycle with all components of the Earth system and to understand how it stimulates and regulates changes on both global and regional scales.
Christy, John R. +6 more
core +1 more source
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source