Results 71 to 80 of about 2,317,544 (334)
Local sensitivity analysis for the Cucker-Smale model with random inputs
, 2017 We present pathwise flocking dynamics and local sensitivity analysis for the Cucker-Smale(C-S) model with random communications and initial data. For the deterministic communications, it is well known that the C-S model can model emergent local and ...
Ha, Seung-Yeal, Jin, Shi
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Global Sensitivity Analysis Method Based on Support Vector Machine
Hangkong gongcheng jinzhan, 2018 Aiming at the difficulties of implicit limit state function and high-computational cost in structural sensitivity analysis, a new method is proposed for structural global sensitivity analysis which is based on support vector machine(SVM) method and Monte
Zhang Hang, Li Hongshuang
doaj +1 more source
A global sensitivity analysis for African sleeping sickness [PDF]
Parasitology, 2010 SUMMARYAfrican sleeping sickness is a parasitic disease transmitted through the bites of tsetse flies of the genusGlossina. We constructed mechanistic models for the basic reproduction number,R0, ofTrypanosoma brucei gambienseandTrypanosoma brucei rhodesiense, respectively the causative agents of West and East African human sleeping sickness.
Alison P. Galvani +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Global Dynamics and Sensitivity Analysis of a Vector-Host-Reservoir Model
Sultan Qaboos University Journal for Science, 2016 The role of animal reservoir in the disease dynamics is not yet properly studied. In the present investigation a mathematical model of a vector-host-reservoir is proposed and analyzed to observe the global dynamics of the disease.
Ibrahim M. ELmojtaba +2 more
doaj +1 more source
An adaptive sampling method for global sensitivity analysis based on least-squares support vector regression [PDF]
, 2018 In the field of engineering, surrogate models are commonly used for approximating the behavior of a physical phenomenon in order to reduce the computational costs.
Bourinet, Jean-Marc +2 more
core
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Machines, 2023 The mounting increase in the technological complexity of modern engineering systems requires compound uncertainty quantification, from a quantitative and qualitative perspective.
Alex Grenyer +3 more
doaj +1 more source
Global Sensitivity Analysis of a Spray Drying Process [PDF]
Processes, 2019 Spray drying is a key unit operation used to achieve particulate products of required properties. Despite its widespread use, the product and process design, as well as the process control remain highly empirical and depend on trial and error experiments.
Bhonsale, Satyajeet Sheetal +2 more
openaire +2 more sources