Results 61 to 70 of about 716,482 (227)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
The Big Burp: A Bad Day in the Paleocene [PDF]
This lesson focuses on global warming and a possible connection with the Paleocene extinction event. Students will explore how a global warming episode associated with the release of methane from methane hydrate deposits could have been responsible for ...
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A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Uncertainty and global warming : an option - pricing approach to policy [PDF]
Uncertainty is inherent in the analysis of global warming issues. Not only is there considerable scientific uncertainty about the magnitude of global warming, but even if that problem were resolved, there is uncertainty about what monetary value to ...
Baranzini, Andrea +2 more
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Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
"International Trade and Global Warming" [PDF]
In a non-cooperative strategic environmental regulation, unilateral regulation may yield the so-called "carbon-leakage" and the government choice over the emission taxes and quotas play an important role.
Jota Ishikawa, Kazuharu Kiyono
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The rogue nature of hiatuses in a global warming climate
Geophysical Research Letters, 2016 The nature of rogue events is their unlikelihood and the recent unpredicted decade‐long slowdown in surface warming, the so‐called hiatus, may be such an event.
F. Sévellec, B. Sinha, N. Skliris
doaj +1 more source
Global Warming: Why is There Debate?
, 2017 Previous studies have produced conflicting results for the determining factors of acceptance or rejection of the science behind the global warming phenomenon; some cite religion as a hindrance to the acceptance of this scientific theory [Kilburn 2008 ...
Smith, Mackenzie E.
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The Semiotics of Global Warming: Combating Semiotic Corrruption [PDF]
, 2007 The central focus of this paper is the disjunction between the findings of climate science in revealing the threat of global warming and the failure to act appropriately to these warnings. The development of climate science can be illuminated through the
Gare, Arran
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