Results 81 to 90 of about 746,378 (333)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Public Policies against Global Warming [PDF]

Judged by the principle of intertemporal Pareto optimality, insecure property rights and the greenhouse effect both imply overly rapid extraction of fossil carbon resources.
Hans-Werner Sinn
core  

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Q&A: Global warming: No easy answers

California Agriculture, 2000
California Agriculture - All ...
F Rowland
doaj  

Reduced spread of simulated global warming patterns among CMIP6 models with elevated level of warming

Environmental Research Letters
Uneven economic impacts of climate change have been largely caused by differentiated warming rates across different geographical regions, affecting the lives of the majority of world’s population. Historical and future warming rates are commonly obtained
Yilin Meng, Yan Yu, Ji Nie
doaj   +1 more source

"Global Warming and Transport Policies" [PDF]

The Japanese government has advocated a wide range of policy measures to reduce greenhouse gas emissions from transportation, e.g. improvements of gas mileage, development of alternative fuel vehicles, shifts to walking, bicycles and public ...
Yoshitsugu Kanemoto
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

global warming

Citation: 'global warming' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14720 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
  +4 more sources

Global Warming – Our Greatest Challenge

Research and Review Journal of Nondestructive Testing
The current state of Earth’s climate is the result of a long-lasting, continuous development: it is a snapshot from a film of the Earth’s history that has lasted around 4.5 billion years and is still running. Climate fluctuations are documented by
Peter Lemke
doaj   +1 more source

Climate extremes in Europe at 1.5 and 2 degrees of global warming

Environmental Research Letters, 2017
There is an international effort to attempt to limit global warming to 1.5 °C above pre-industrial levels, however, there is a lack of quantitative analysis on the benefits of holding global warming to such a level.
Andrew D King, David J Karoly
doaj   +1 more source