Results 131 to 140 of about 74,517 (259)

Impact of Voxelotor on Red Blood Cell Exchange Therapeutic Procedures: Evaluation of Multi‐Institutional Procedure Data

open access: yesJournal of Clinical Apheresis, Volume 40, Issue 3, June 2025.
ABSTRACT Hemoglobin S (HbS) polymerization inhibitor drugs such as voxelotor can result in a split peak in HbS as well as additional peaks with hemoglobin A in quantitative methods of HbS measurement. It is unclear how these results should be used to make transfusion decisions.
Sally Campbell‐Lee   +5 more
wiley   +1 more source

Enhancing Cognitive Workload Classification Using Integrated LSTM Layers and CNNs for fNIRS Data Analysis [PDF]

open access: yesarXiv
Functional near-infrared spectroscopy (fNIRS) is employed as a non-invasive method to monitor functional brain activation by capturing changes in the concentrations of oxygenated haemoglobin (HbO) and deoxygenated haemo-globin (HbR). Various machine learning classification techniques have been utilized to distinguish cognitive states.
arxiv  

Kinetic Evidence for the Existence of α‐Globin Pool in β‐Thalassemic Reticulocytes [PDF]

open access: bronze, 1968
A. Bargellest   +4 more
openalex   +1 more source

Optimisation of the Danish national haemoglobinopathy screening programme – A prospective intervention study

open access: yeseJHaem, Volume 6, Issue 3, June 2025.
Abstract Introduction The Danish national haemoglobinopathy screening programme offers screening to at‐risk pregnant women. Despite efforts to increase awareness of the screening programme, most women in the target population remain unscreened. In contrast, > 90% of pregnant women in Denmark attend a screening for chromosomal abnormalities by combined ...
Esther Agnethe Ejskjær Gravholt   +6 more
wiley   +1 more source

Light Scattering and Sedimentation of Native Human Adult and Fetal Globin

open access: hybrid, 1959
A. Rossi‐Fanelli   +2 more
openalex   +1 more source

BdNRT2A and BdNRT3.2 Are the Major Components of the High‐Affinity Nitrate Transport System in Brachypodium distachyon

open access: yesPlant Direct, Volume 9, Issue 6, June 2025.
ABSTRACT An efficient nitrate uptake system contributes to the improvement of crop nitrogen use efficiency under low nitrogen availability. The High Affinity nitrate Transport System (HATS) in plants is active in low range of external nitrate and is mediated by a two‐component system (high affinity transporters NRT2 associated to a partner protein NRT3
Laure C. David   +10 more
wiley   +1 more source

The wider perspective: Barriers and recommendations for transfusion support for patients with sickle cell disease in low‐ and middle‐income countries

open access: yesBritish Journal of Haematology, Volume 206, Issue 6, Page 1585-1592, June 2025.
Globally, sickle cell disease (SCD) is the most common inherited haemoglobinopathy. The highest burden of SCD is encountered in low‐ and middle‐income countries (LMICs), most of which lack the resources to contend with the disease. Blood transfusion remains central to the emergent treatment and prevention of complications of SCD.
Jeremy W. Jacobs   +13 more
wiley   +1 more source

Long‐term efficacy and safety of mitapivat in non‐transfusion‐dependent α‐ or β‐thalassaemia: An open‐label phase 2 study

open access: yesBritish Journal of Haematology, Volume 206, Issue 6, Page 1764-1773, June 2025.
Mitapivat is an oral activator of pyruvate kinase (PK), the enzyme responsible for the final step in glycolysis, and increases production of adenosine triphosphate (ATP), which may lead to improvements in red blood cell health, ineffective erythropoiesis and haemolysis.
Kevin H. M. Kuo   +9 more
wiley   +1 more source

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