Results 121 to 130 of about 94,653 (246)
Glia, Volume 74, Issue 12, December 2026.Müller glia and the retinal pigment epithelium interact around cone outer segment in the subretinal space of both zebrafish and mouse. The contacts are established early during development but subsequent to outer segment emergence. ABSTRACT Homeostasis of the vertebrate retina critically depends on two non‐neuronal cell populations, Müller glia and the
Maria Sharkova +6 more
wiley +1 more source
Expression of human β-globin genes in knock-in mice.
, 2019 (A) Total RNA was prepared from spleens of 1-month-old anemic mice (N = 4 for each genotype). Expression levels of the human β(γ)- or β(ε)-globin genes (analyzed by common primer set targeted at β-globin sequence; BT-4S1 and BT-4A1) and endogenous mouse ...
Aki Ushiki (3353537) +5 more
core +1 more source
Expanding the Utility of Exome Sequencing in Preventive and Population Genetics
American Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2433-2442, November 2026.ABSTRACT Carrier screening is a long‐standing genetic testing process offered to at‐risk couples, with or without a family history, who might have pregnancies affected by an autosomal recessive (AR) or X‐linked (XL) disorder. A total of 276 unrelated individuals, initially referred for rare disorder screening by clinicians, were enrolled in this study ...
Charilaos Kostoulas +6 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.An enantioselective photometallobiocatalytic cross‐coupling of pyridotriazoles and secondary alkyltrifluoroborate salts is developed. Cooperative catalysis using eosin B and an engineered protoglobin combines visible‐light‐mediated radical generation with enzymatic metal carbenoid activation, affording valuable N‐heterocyclic products in excellent ...
Huanan Wang +5 more
wiley +2 more sources
The Maintenance of Dysmyelinated Small‐Diameter Axons by 14‐3‐3s in the Central Nervous System
Glia, Volume 74, Issue 11, November 2026.Dysmyelinated small‐diameter axons are maintained in teneurin‐4 deficient mice at the age of 1 year, while axonal damage is observed. 14‐3‐3s are highly expressed and suppress the progression of the damage in these axons. ABSTRACT In the central nervous system, myelin formed around nerve axons by oligodendrocyte enables efficient conduction of action ...
Nanako Yamada +15 more
wiley +1 more source
Quality control: globin levels in arrays.
, 2014 Data were GCRMA normalised and levels of 3 representative alpha globin probe sets (A, B and C) and one beta probe set (D) were averaged for each condition.
Janine Kirby (251349) +6 more
core +1 more source
HPV125‐induced generalized verrucosis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sven Niklas Burmann +7 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
CRISPR/Cas9-mediated γ-globin expression upregulation in HEK293T cells
Guangxi Yike Daxue xuebaoObjective To edit the γ-globin promoter of HEK293T cells using the CRISPR/Cas9 technology to upregulate γ-globin and explore the feasibility of using gene editing technology for the treatment of β-thalassemia.
HUANG Xianjuan, LAI Yongrong, LI Jing
doaj +1 more source
, 2017 Background Increase of the expression of γ-globin gene and high production of fetal hemoglobin (HbF) in β-thalassemia patients is widely accepted as associated with a milder or even asymptomatic disease.
Roberto Gambari +21 more
core +1 more source