Results 111 to 120 of about 82,601 (269)

Penetration studies of blood globin gels

open access: yes, 1985
Studies were made on the effect of temperature, pH and protein and salt concentration on the penetration force withstood by globin gels. The registered force increased with heating temperature (60-95°C) and protein concentration (1.4-5.0%).
Autio, Karin   +7 more
core   +1 more source

Acute pain transfusion reaction in a patient with thalassemia: In‐depth characterization of short‐ and long‐term phenotypes

open access: yesTransfusion, EarlyView.
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa   +20 more
wiley   +1 more source

Rare antigen‐negative red blood cells from pluripotent stem cells for precision transfusion medicine

open access: yesTransfusion, EarlyView.
Abstract Background Blood bank identification of antibodies against high‐prevalence antigens remains a challenge due to the scarcity of antigen‐negative reagent red cells sourced from blood donors. The MAM antigen, encoded by EMP3, is one such antigen associated with red cell alloimmunization and hemolytic disease of the fetus and newborn. Study Design
Naomi Gunawardena   +9 more
wiley   +1 more source

A multi‐omics investigation of sarcopenia and frailty: Integrating genomic, epigenomic and telomere length data

open access: yesExperimental Physiology, EarlyView.
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė   +10 more
wiley   +1 more source

The 3' terminal sequences of human alpha and beta globin messenger RNAs: comparison with rabbit globin messenger RNA.

open access: yes, 1976
Sequences of 43 and 70 nucleotides adjacent to the 3' terminal poly(A) of human alpha and beta globin mRNAs have been established. Sequence analysis of complementary DNA from both normal and thalassemic globin mRNA preparations was carried out using ...
Longley, JI   +2 more
core   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida   +4 more
wiley   +1 more source

Relationships between globin chains of branchiopoda (crustacea)

open access: yes, 1992
: Different Branchiopod hemoglobins were found to have a heterogeneous globin chain composition. Amino terminal sequencing and peptide mapping were used to compare different globin chains. Two-domain globin chains (Cladocera and Conchostraca) do not form
Peeters, Karin   +2 more
core  

Beta-globin sequence data

open access: yes, 2015
DNA sequences of the Beta-globin ...
Erik Wapstra (314066)   +5 more
core   +1 more source

The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia in high‐altitude deer mice (Peromyscus maniculatus)

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia has been contentious. Many high‐altitude natives have greater haemoglobin–O2 affinity (lower P50, the O2 pressure at 50% haemoglobin saturation) than their low‐altitude counterparts, but the advantages of this change for aerobic metabolism have often remained
Kayla M. Garvey, Graham R. Scott
wiley   +1 more source

The mouse globin pseudogene beta h3 is descended from a premammalian delta-globin gene.

open access: yes, 1984
The beta h3 pseudogene of the BALB/c mouse contains sequence defects which prevent transcription and translation to produce a beta-globin. Comparison with other globin gene sequences indicates that beta h3 arose by recombination between an adult beta ...
Hardies, Stephen   +4 more
core   +1 more source

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