Results 171 to 180 of about 82,601 (269)

Neuregulin‐1 Mitigates Kidney Injury in Humanized Sickle Cell Mice

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Compared with untreated sickle cell (HbSS) mice, neuregulin‐1 (NRG‐1) treatment reduced plasma heme, lactate dehydrogenase, and pro‐inflammatory cytokines while increasing the proportion of circulating F‐cells. NRG‐1 improved urinary biomarkers of kidney health, decreasing cystatin C and NGAL levels and increased renal repair markers clusterin and ...
William K. Agbozo, Wesley Solomon, Isaac Joe Erskine, Cecilia E. Lekpor, Oguljahan Babayewa, Alaijah Bashi, Adriana Harbuzariu, Aqua Asberry, Driss Adel, Samuel Adjei, Lily Paemka, Solomon F. Ofori‐Acquah, Jonathan K. Stiles   +12 more
wiley   +1 more source

The Journey of Gene Therapy in Sickle Cell Disease: How Molecular Advances Meet Clinical Care. [PDF]

Cells
Tardif M, Saby M, Forté S, Pincez T.
europepmc   +1 more source

Targeted protein degradation for fetal hemoglobin induction: a new paradigm in β-hemoglobinopathy therapy. [PDF]

Biomark Res
Arji S, Shen Z, Welch S, ElMahdaoui F, Bahadur A, Lee E, Lee H, Wu SP, Konshina E, Ayubali B, Tenen D, Chai L, Liu J.   +12 more
europepmc   +1 more source

Initiation of globin synthesis

FEBS Letters, 1972
Crystal, R.G., Nienhuis, A.W., Prichard, P.M., Picciano, D., Elson, N.A., Merrick, W.C., Graf, H., Shafritz, D.A., Laycock, D.G., Last, J.A., Anderson, W.F.   +10 more
openaire   +2 more sources

Polynucleotide Analysis of Human Globin Variants

, 1980
In a search for open reading frames in several known polynucleotide sequences of structural genes, we found that the anti-sense strand of the β and ε human, α and β rabbit globin DNA fragments contain translatable sequences even longer than the coding ...
V. SCARLATO, A. CASCINO, M. CIPOLLARO, MASTROCINQUE, GIUSEPPE   +3 more
core  

Prenatal Diagnosis of Compound Heterozygous Beta-Thalassemia: A Report of Two Cases. [PDF]

Cureus
Jha S, Jha S, Jha VC, Narayan A, Bhagat R.   +4 more
europepmc   +1 more source

Genetic polymorphism of SNPs rs9399137 and rs4895441in HBS1L-MYB and SNP rs766432 in BCL11A among β-thalassemia Egyptian patients. [PDF]

BMC Genom Data
Abdelrahman AA, Talaat RM, El-Halfawy IA, Alalwi MR, Rizk DMY.   +4 more
europepmc   +1 more source

Daprodustat augments red cell and γ-globin production in models of sickle cell disease. [PDF]

Blood Red Cells Iron
Sharma M, Ishfaq M, Mondal P, Mohideen A, Chowdhury FA, Taiclet S, Philips BJ, Crosby D, Wood KC, Straub AC, Ghosh S, Yien YY, Xu JZ.   +12 more
europepmc   +1 more source

A note on denatured globin [PDF]

Biochemical Journal, 1932
openaire   +2 more sources

ASF1B promotes erythropoiesis by regulating the establishment and enrichment of H3.3 nucleosomes. [PDF]

Nucleic Acids Res
Liu J, Song X, Zhou L, Zhao Y, Kim J, Li J, Dean A, Guo X.   +7 more
europepmc   +1 more source