Results 151 to 160 of about 82,601 (269)

Hepatic Enzyme Abnormalities and Their Association With Hematological Parameters in Sickle Cell Disease: A Case‐Control Study in Cameroon

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims The polymerization of deoxygenated hemoglobin S, resulting from a genetic mutation in sickle cell disease (SCD), leads to damage in multiple organs, including renal, cardiopulmonary, and cerebrovascular systems. The liver is also commonly affected, resulting in “sickle cell liver disease,” which may lead to progressive ...
Josué Louokdom Simo, Prisca Tipane Angandji, Romaric De Manfouo Tuono, Kabrel Fandouo Njinjou, Ingrid Worti Sulem Yong, Maryline Seuko Njopwouo, Pascal Dieudonne Djamen Chuisseu   +6 more
wiley   +1 more source

Oral Cryptococcosis due to Naganishia diffluens in a Patient With Thalassemia: A Case Report and a Literature Review

Journal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh, Zeynab Haseli, Javad Javidnia, Mahdi Abastabar, Eisa Nazar, Hosein Jalali, Mohamad Taghi Hedayati, Hossein Karami, Mohsen Nosratabadi, Lotfollah Davoodi, Seyyed Reza Aghili, Maryam Moazeni, Iman Haghani, Hamid Badali   +13 more
wiley   +1 more source

Development of a Clinical Severity Score for Indian Sickle Cell Anaemia Patients

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background Sickle cell anaemia (SCA) is a monogenic disorder but shows variable disease severity. We evaluated the utility of paediatric severity scores (PSS) in Indian patients and developed two modified scores: Indian Severity Score 1 (ISS1) by adding four clinical parameters to PSS, and ISS2 by excluding four biochemical measures from ISS1.
Suraj S. Nongmaithem, Amitabh Biswas, Swaroop Iyer, Jandhayala Vyshnavi, Archana Wath, Giriraj R. Chandak, Dipty Jain   +6 more
wiley   +1 more source

Validation of Gazelle Microchip Electrophoresis for Premarital Hemoglobinopathy Screening in Türkiye

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Introduction Hemoglobinopathies, the most prevalent recessive monogenic disorders globally, encompass thalassemia syndromes and structural hemoglobin variants, affecting approximately 5% of the world's population as carriers, with around 315,000 affected births annually.
Duran Canatan, Serpil Delibaş, Emel Altunsoy, Elif Gözde Gökkaya, Sultan Aydın, Defne Ay Tuncel, Rucha Natu, Priyaleela Thota, Umut A. Gurkan   +8 more
wiley   +1 more source

Transcranial Doppler Ultrasound Velocity Measurements in Children With Sickle Cell Disease in Kenya

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background Sickle cell disease (SCD) is the most common inherited haemoglobinopathy and poses a high public health burden in Sub‐Saharan Africa. Children with sickle cell anaemia are at a highrisk of ischemic stroke, and transcranial Doppler (TCD) ultrasonography helps identify those at highest risk for primary stroke prevention.
Catherine Mwalimu, Oscar Odhiambo, Elaine Mashisia, Teresa Mwanja, Allan Ade, Maria Vittoria De Vita, Katherine Oyieke, Pauline Samia, Fenella Kirkham, Samson Gwer   +9 more
wiley   +1 more source

PGC-1α agonism via oral administration of ZLN005 induces fetal hemoglobin and is antisickling in sickle mice. [PDF]

Blood Adv
Benmhammed H, Sun Y, AlAbdullatif S, Chen A, Khan S, Zadeh AM, Mazile N, Beacham GM, Mahdaviani K, Williams C, Alekseyev YO, Campbell JD, Hagedorn EJ, Heaphy C, Klings ES, Steinberg MH, Cui S.   +16 more
europepmc   +1 more source

Association Between Micronutrients and Cognitive Performance Among Adolescents and Young Adults Living With Sickle Cell Disease in Kumasi, Ghana: A Cross‐Sectional Study

eJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Aim Cognitive deficits are commonly reported in patients with sickle cell disease (SCD). Dietary micronutrient intake is a potential modifiable risk factor whose relationship with cognition in SCD patients remains poorly characterised. This study aimed to determine the association between dietary micronutrient intake and cognition among these ...
Albert Dennis Kegya, Mary Amoako, Vivian Paintsil, Kwame Nana Ayisi‐Boateng, Clement Kubreziga Kubuga   +4 more
wiley   +1 more source

The Molecular Pathology of Non-Malignant Haematological Disease. [PDF]

Br J Biomed Sci
Blann AD, Dunn RG.
europepmc   +1 more source

Growth of Oxygen Environment of the Newborn Vocal Fold Maculae Flavae as a Stem Cell Niche

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objectives Accumulating evidence indicates that the anterior and posterior maculae flavae of the human vocal fold mucosa function as niches for tissue stem cells. This study aimed to characterize the oxygen microenvironment of the maculae flavae in the newborn vocal fold and to clarify its potential involvement in metabolic regulation and the ...
Kiminori Sato, Shun‐ichi Chitose, Fumihiko Sato, Kiminobu Sato, Takeharu Ono, Hirohito Umeno   +5 more
wiley   +1 more source

Molecular analysis of beta-globin gene mutations among Thai beta-thalassemia children: results from a single center study

, 2014
Boonchai Boonyawat,1 Chalinee Monsereenusorn,2 Chanchai Traivaree2 1Division of Genetics, Department of Pediatrics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand; 2Division of Hematology/Oncology, Department of Pediatrics ...
Boonyawat B, Traivaree C, Monsereenusorn C   +2 more
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