Results 151 to 160 of about 136,712 (243)
ABSTRACT Background Congenital methemoglobinemia caused by hemoglobin variants is a rare hematological disorder often misdiagnosed due to overlapping features with enzymatic defects. Hb Tübingen, a β‐globin chain variant (βCD106), is characterized by increased autoxidation, heat instability, and cyanosis.
Hualei Luo +7 more
wiley +1 more source
ABSTRACT Little is known about natural humoral immunity against recurrent HPV DNA detection. The objective of this study was to asses the risk of cervical HPV16 DNA detection in unvaccinated women according to HPV16 IgG and IgM seroreactivity status. We analyzed data from 618 women (mean age of 32 years) participating in the Ludwig–McGill cohort. Women
Andrea Trevisan +5 more
wiley +1 more source
ABSTRACT Squamous cell carcinoma of the anus (SCCA), caused by high‐risk human papillomavirus (HR‐HPV) genotypes, is a growing concern among gay, bisexual, and other men who have sex with men and transgender individuals, particularly those living with HIV.
Leila Ferrera +12 more
wiley +1 more source
Does Sickle Cell Anaemia Have a Relationship With Avascular Pulp Necrosis? A Systematic Review
ABSTRACT This systematic review examined the relationship between sickle cell disease (SCD), an inherited genetic hemoglobinopathy, and avascular pulp necrosis (APN) in intact teeth. A comprehensive search of eight electronic databases was performed up to December 2024.
Elidiane Elias Ribeiro +5 more
wiley +1 more source
A century of theories of balancing selection
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka +10 more
wiley +1 more source
Sutimlimab in Patients With Cold Agglutinin Disease (CAD): Results From a Managed Access Program
ABSTRACT Cold agglutinin disease (CAD) is a low‐grade lymphoproliferative disorder accounting for 15%–30% of patients suffering from autoimmune hemolytic anemias. The clonal B cells produce autoantibodies primarily of the IgM‐κ class that cause agglutination of red blood cells (RBCs) at temperatures ≤ 37°C and activate the classical complement pathway ...
Sandra Maria Frey +5 more
wiley +1 more source
Making Molecular Diagnostics Faster
ABSTRACT Background Over the past 40 years, molecular diagnostic methods have evolved from multi‐step, time‐consuming protocols towards either rapid targeted tests or expansive, massively parallel testing. Aims Here we consider the speed limits of targeted molecular diagnostics, considering the three sequential required steps: nucleic acid preparation,
Carl T. Wittwer +5 more
wiley +1 more source
HbSC disease: Not as benign as you think
HemaSphere, Volume 10, Issue 4, April 2026.
Edeghonghon Olayemi
wiley +1 more source

