Results 11 to 20 of about 74,419 (163)

RNA Sequencing (RNA-Seq) Reveals Extremely Low Levels of Reticulocyte-Derived Globin Gene Transcripts in Peripheral Blood From Horses (Equus caballus) and Cattle (Bos taurus)

open access: yesFrontiers in Genetics, 2018
RNA-seq has emerged as an important technology for measuring gene expression in peripheral blood samples collected from humans and other vertebrate species.
Carolina N. Correia   +9 more
doaj   +1 more source

Prevalence and genetic analysis of triplicated α-globin gene in Ganzhou region using high-throughput sequencing

open access: yesFrontiers in Genetics, 2023
α-globin gene triplication carriers were not anemic in general, while some studies found that α-globin gene triplication coinherited with heterozygous β-thalassemia may cause adverse clinical symptoms, which yet lacks sufficient evidence in large ...
Xinxing Xie   +22 more
doaj   +1 more source

A etimologia de biomoléculas com metais de transição como auxiliar na aprendizagem de Química Biológica

open access: yesQuímica Nova, 2013
Numerous functional biomolecules are associated with metals, i.e. the metallobiomolecules; more specifically, some are dependent on transition metals required for several crucial biological roles.
José A. L. da Silva
doaj   +1 more source

3,3′,5-Triiodothyroacetic acid (TRIAC) induces embryonic ζ-globin expression via thyroid hormone receptor α

open access: yesJournal of Hematology & Oncology, 2021
The human ζ-globin gene (HBZ) is transcribed in primitive erythroid cells only during the embryonic stages of development. Reactivation of this embryonic globin synthesis would likely alleviate symptoms both in α-thalassemia and sickle-cell disease ...
Huiqiao Chen   +10 more
doaj   +1 more source

Distribution of cytoglobin in the mouse brain

open access: yesFrontiers in Neuroanatomy, 2016
Cytoglobin (Cygb) is a vertebrate globin with so far poorly defined function. It is expressed in the fibroblast cell-lineage but has also been found in neurons.
Stefan eReuss   +4 more
doaj   +1 more source

Gene Algebra from a Genetic Code Algebraic Structure [PDF]

open access: yesJournal of Mathematical Biology. 2005 Oct;51(4):431-57., 2004
The biological distinction between the base positions in the codon, the chemical types of bases (purine and pyrimidine) and their hydrogen bond number have been the most relevant codon properties used in the genetic code analysis. Now, these properties have allowed us to build a Genetic Code ring isomorphic to the ring (Z64, +,*) of the integer module ...
arxiv   +1 more source

Effect of dietary globin, a natural emulsifier, on the growth performance and digestive efficiency of broiler chickens

open access: yesItalian Journal of Animal Science, 2019
The feed utilisation of young chicks is characterised by a suboptimal fat digestibility, which can be improved by means of dietary emulsifiers. The objective of this study was to evaluate the effect of dietary Globin on the energy efficiency and ...
Sihem Dabbou   +11 more
doaj   +1 more source

Primitive and definitive erythropoiesis in mammals

open access: yesFrontiers in Physiology, 2014
Red blood cells (RBCs), which constitute the most abundant cell type in the body, come in two distinct flavors- primitive and definitive. Definitive RBCs in mammals circulate as smaller, anucleate cells during fetal and postnatal life, while primitive ...
James ePalis
doaj   +1 more source

A dual reporter mouse model of the human β-globin locus: applications and limitations. [PDF]

open access: yesPLoS ONE, 2012
The human β-globin locus contains the β-like globin genes (i.e. fetal γ-globin and adult β-globin), which heterotetramerize with α-globin subunits to form fetal or adult hemoglobin.
Petros Papadopoulos   +8 more
doaj   +1 more source

A unified statistical model of protein multiple sequence alignment integrating direct coupling and insertions [PDF]

open access: yesBiophysics and Physicobiology Vol. 13, pp. 45-62 (2016), 2015
The multiple sequence alignment (MSA) of a protein family provides a wealth of information in terms of the conservation pattern of amino acid residues not only at each alignment site but also between distant sites. In order to statistically model the MSA incorporating both short-range and long-range correlations as well as insertions, I have derived a ...
arxiv   +1 more source

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