Results 21 to 30 of about 151,779 (318)

Effect of dietary globin, a natural emulsifier, on the growth performance and digestive efficiency of broiler chickens

Italian Journal of Animal Science, 2019
The feed utilisation of young chicks is characterised by a suboptimal fat digestibility, which can be improved by means of dietary emulsifiers. The objective of this study was to evaluate the effect of dietary Globin on the energy efficiency and ...
Sihem Dabbou, Achille Schiavone, Francesco Gai, Silvia Martinez, Josefa Madrid, Fuensanta Hernandez, Andrés L. Martínez Marín, Dominga Soglia, Stefano Sartore, Isabelle D. Kalmar, Laura Gasco, Joana Nery   +11 more
doaj   +1 more source

A simple, highly efficient method for heterologous expression in mammalian primary neurons using cationic lipid-mediated mRNA transfection

Frontiers in Neuroscience, 2010
Expression of heterologous proteins in adult mammalian neurons is a valuable technique for the study of neuronal function. The postmitotic nature of mature neurons prevents effective DNA transfection using simple, cationic lipid-based methods.
Damian J Williams, Henry L Puhl, Stephen R Ikeda   +2 more
doaj   +1 more source

The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]

, 1985
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael, Calendar, R., Dorsch-Häsler, Karoline, Fleckenstein, Bernhard, Gold, L., Jahn, Gerhard, Rüger, Rüdiger, Schaffner, Walter, Stoerker, Jay, Weber, Frank   +9 more
core   +1 more source

Gelling Properties of Globin-Succinylated Globin Conjugates.

NIPPON SHOKUHIN KOGYO GAKKAISHI, 1993
2種類のグロビン-サクシニル化グロビン複合体(CMHTとCUT)を調製し,各複合体のゲル特性について検討した.(1) CMHTはGの配合比率が高くなる程ゲル形成pHは中性の方へ拡大した.例えば, GとSGの配合率が3:7の場合,ゲル形成pHは2.0であったが,G:SG=9:1の場合,ゲルはpH 2.0～3.5の範囲で形成された.一方, G:SGの配合比率が7:3と9:1のCUTの場合,ゲル形成pHは極めて狭い範囲に限定された.(2) ゲルの透明度はCMHT, CUTともにより酸性側で高く,また,グロビンの配合比率が高くなる程透明度も高くなる傾向を示した.(3) 複合体ゲルのゲル強度を測定した. CMHTの場合, G:SG=5:5 (pH 2.0)で高いゲル強度が得られた.
Yuji MIYAGUCHI, Toyoo NAKAMURA, Satoru TAKABATAKE, Masami YONEKURA, Masakazu TSUTSUMI   +4 more
openaire   +2 more sources

Primitive and definitive erythropoiesis in mammals

Frontiers in Physiology, 2014
Red blood cells (RBCs), which constitute the most abundant cell type in the body, come in two distinct flavors- primitive and definitive. Definitive RBCs in mammals circulate as smaller, anucleate cells during fetal and postnatal life, while primitive ...
James ePalis
doaj   +1 more source

Krüppel-Like Transcription Factor KLF1 Is Required for Optimal γ- and β-Globin Expression in Human Fetal Erythroblasts. [PDF]

PLoS ONE, 2016
In human adult erythroid cells, lower than normal levels of Krüppel-like transcription factor 1 (KLF1) are generally associated with decreased adult β- and increased fetal γ-globin gene expression. KLF1 also regulates BCL11A, a known repressor of adult γ-
Divya S Vinjamur, Yousef N Alhashem, Safa F Mohamad, Parth Amin, David C Williams, Joyce A Lloyd   +5 more
doaj   +1 more source

Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences. [PDF]

, 2020
Hematopoietic stem cell gene therapy is a promising approach for treating disorders of the hematopoietic system. Identifying combinations of cis-regulatory elements that do not impede packaging or transduction efficiency when included in lentiviral ...
Aleshe, Bamidele, Ayoub, Paul George, Brown, Devin, Hollis, Roger P, Kohn, Donald B, Kurita, Ryo, Lathrop, Lindsay, Ma, Feiyang, Morgan, Richard A, Nakamura, Yukio, Pellegrini, Matteo, Senadheera, Shantha, Tam, Curtis, Unti, Mildred J, Wong, Ryan L   +14 more
core   +1 more source

A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]

, 1985
A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael, Dorsch-Häsler, Karoline, Fleckenstein, Bernhard, Jahn, Gerhard, Schaffner, Walter, Weber, Frank   +5 more
core   +1 more source

Physiological and Aberrant γ-Globin Transcription During Development

Frontiers in Cell and Developmental Biology, 2021
The expression of the fetal Gγ- and Aγ-globin genes in normal development is confined to the fetal period, where two γ-globin chains assemble with two α-globin chains to form α2γ2 tetramers (HbF). HbF sustains oxygen delivery to tissues until birth, when
Gloria Barbarani, Agata Labedz, Sarah Stucchi, Alessia Abbiati, Antonella E. Ronchi   +4 more
doaj   +1 more source

Revealing mammalian evolutionary relationships by comparative analysis of gene clusters [PDF]

, 2012
Many software tools for comparative analysis of genomic sequence data have been released in recent decades. Despite this, it remains challenging to determine evolutionary relationships in gene clusters due to their complex histories involving ...
Abi-Rached, Akahoshi, Bailey, Benjamin Dickins, Birney, Cadavid, Cathy Riemer, Chen, Chih-Hao Hsu, Chiu, Colobran, Datta, Degenhardt, Dewey, Dufayard, Edwards, Eric D. Green, Fitch, Fitch, Fitch, Giltae Song, Gish, Gonzalez, Goodstadt, Graef, Guethlein, Guethlein, Han, Hardies, Hardison, Hardison, Hardison, Harris, Hie Lim Kim, Hoffmann, Hou, Hou, Hsu, Hsu, Hu, Huerta-Cepas, Jensen, Johnson, Kim, Kristensen, Lee, Levy, Li, Li, Lopez-Vazquez, Louxin Zhang, Margulies, Martin, Matsuya, Mi, Miyata, Muller, Murphy, NISC Comparative Sequencing Program, , Opazo, Opazo, Ostlund, Ouzounis, Parham, Pianezza, Rajalingam, Ross C. Hardison, Sambrook, Shilling, Siepel, Smit, Song, Song, Song, Sonnhammer, Su, Tatusov, The ENCODE Project Consortium, Uchiyama, van der Heijden, Vilella, Wang, Wapinski, Waterhouse, Webb Miller, Wilson, Wilson, Woelk, Yu Zhang, Zhang   +89 more
core   +2 more sources