Results 21 to 30 of about 147,500 (287)
TMEM8 – a non-globin gene entrapped in the globin web [PDF]
For more than 30 years it was believed that globin gene domains included only genes encoding globin chains. Here we show that in chickens, the domain of alpha-globin genes also harbor the non-globin gene TMEM8. It was relocated to the vicinity of the alpha-globin cluster due to inversion of an approximately 170-kb genomic fragment.
Elena S. Philonenko+5 more
openaire +3 more sources
Morphologic and Electrophoretic Features of Hemoglobin Bart's Hydrops Fetalis. [PDF]
eJHaem, Volume 6, Issue 4, August 2025.
Amid A, Turley E, Au N, Setiadi A.
europepmc +2 more sources
The folding pathway for globins [PDF]
Previous investigations have successfully predicted the three-dimensional structures of trypsin inhibitor [ 1,2] , myoglobin [3,4] , TMV protein [ 51 and rubredoxin [2]. Using mechanisms of protein chain folding which one of us [5 $1 suggested,.we can find a common folding pathway for the globins which are included in the ‘Atlas of Protein Sequence and
V.I. Lim, Alexander V. Efimov
openaire +3 more sources
Analysis of β-globin chromatin micro-environment using a novel 3C variant, 4Cv [PDF]
Copyright: © 2010 Pink et al.Higher order chromatin folding is critical to a number of developmental processes, including the regulation of gene expression.
Christopher H Eskiw+4 more
core +3 more sources
Quality Assurance in Cervical Cancer Screening: Evaluation of Sample Adequacy in HPV DNA Testing. [PDF]
ABSTRACT In HPV‐primary screening, sample quality significantly influences test accuracy. Unlike cytology‐based screening, no consensus guidelines presently exist for sample quality assessment in HPV testing. This study aims to evaluate the impact of sample cellularity on HPV testing.
d'Avenia M+7 more
europepmc +2 more sources
Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity [PDF]
Genomic maps of chromatin modifications have provided evidence for the partitioning of genomes into domains of distinct chromatin states, which assist coordinated gene regulation.
Hair, A.+3 more
core +10 more sources
Numerous functional biomolecules are associated with metals, i.e. the metallobiomolecules; more specifically, some are dependent on transition metals required for several crucial biological roles.
José A. L. da Silva
doaj +1 more source
RNA-seq has emerged as an important technology for measuring gene expression in peripheral blood samples collected from humans and other vertebrate species.
Carolina N. Correia+9 more
doaj +1 more source
α-globin gene triplication carriers were not anemic in general, while some studies found that α-globin gene triplication coinherited with heterozygous β-thalassemia may cause adverse clinical symptoms, which yet lacks sufficient evidence in large ...
Xinxing Xie+22 more
doaj +1 more source
The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. [PDF]
Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the β-globin transgene.
Baldwin, Kismet M+12 more
core +4 more sources