Results 21 to 30 of about 147,500 (287)

TMEM8 – a non-globin gene entrapped in the globin web [PDF]

open access: yesNucleic Acids Research, 2009
For more than 30 years it was believed that globin gene domains included only genes encoding globin chains. Here we show that in chickens, the domain of alpha-globin genes also harbor the non-globin gene TMEM8. It was relocated to the vicinity of the alpha-globin cluster due to inversion of an approximately 170-kb genomic fragment.
Elena S. Philonenko   +5 more
openaire   +3 more sources

Morphologic and Electrophoretic Features of Hemoglobin Bart's Hydrops Fetalis. [PDF]

open access: yesEJHaem
eJHaem, Volume 6, Issue 4, August 2025.
Amid A, Turley E, Au N, Setiadi A.
europepmc   +2 more sources

The folding pathway for globins [PDF]

open access: yesFEBS Letters, 1977
Previous investigations have successfully predicted the three-dimensional structures of trypsin inhibitor [ 1,2] , myoglobin [3,4] , TMV protein [ 51 and rubredoxin [2]. Using mechanisms of protein chain folding which one of us [5 $1 suggested,.we can find a common folding pathway for the globins which are included in the ‘Atlas of Protein Sequence and
V.I. Lim, Alexander V. Efimov
openaire   +3 more sources

Analysis of β-globin chromatin micro-environment using a novel 3C variant, 4Cv [PDF]

open access: yes, 2010
Copyright: © 2010 Pink et al.Higher order chromatin folding is critical to a number of developmental processes, including the regulation of gene expression.
Christopher H Eskiw   +4 more
core   +3 more sources

Quality Assurance in Cervical Cancer Screening: Evaluation of Sample Adequacy in HPV DNA Testing. [PDF]

open access: yesJ Med Virol
ABSTRACT In HPV‐primary screening, sample quality significantly influences test accuracy. Unlike cytology‐based screening, no consensus guidelines presently exist for sample quality assessment in HPV testing. This study aims to evaluate the impact of sample cellularity on HPV testing.
d'Avenia M   +7 more
europepmc   +2 more sources

Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity [PDF]

open access: yes, 2011
Genomic maps of chromatin modifications have provided evidence for the partitioning of genomes into domains of distinct chromatin states, which assist coordinated gene regulation.
Hair, A.   +3 more
core   +10 more sources

A etimologia de biomoléculas com metais de transição como auxiliar na aprendizagem de Química Biológica

open access: yesQuímica Nova, 2013
Numerous functional biomolecules are associated with metals, i.e. the metallobiomolecules; more specifically, some are dependent on transition metals required for several crucial biological roles.
José A. L. da Silva
doaj   +1 more source

RNA Sequencing (RNA-Seq) Reveals Extremely Low Levels of Reticulocyte-Derived Globin Gene Transcripts in Peripheral Blood From Horses (Equus caballus) and Cattle (Bos taurus)

open access: yesFrontiers in Genetics, 2018
RNA-seq has emerged as an important technology for measuring gene expression in peripheral blood samples collected from humans and other vertebrate species.
Carolina N. Correia   +9 more
doaj   +1 more source

Prevalence and genetic analysis of triplicated α-globin gene in Ganzhou region using high-throughput sequencing

open access: yesFrontiers in Genetics, 2023
α-globin gene triplication carriers were not anemic in general, while some studies found that α-globin gene triplication coinherited with heterozygous β-thalassemia may cause adverse clinical symptoms, which yet lacks sufficient evidence in large ...
Xinxing Xie   +22 more
doaj   +1 more source

The human ankyrin 1 promoter insulator sustains gene expression in a β-globin lentiviral vector in hematopoietic stem cells. [PDF]

open access: yes, 2015
Lentiviral vectors designed for the treatment of the hemoglobinopathies require the inclusion of regulatory and strong enhancer elements to achieve sufficient expression of the β-globin transgene.
Baldwin, Kismet M   +12 more
core   +4 more sources

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