Results 11 to 20 of about 82,601 (269)
The globin gene family of the cephalochordate amphioxus: implications for chordate globin evolution [PDF]
BMC Evolutionary Biology, 2010 Background The lancelet amphioxus (Cephalochordata) is a close relative of vertebrates and thus may enhance our understanding of vertebrate gene and genome evolution.
Marden Michael C +6 more
doaj +6 more sources
Globin and Globin Gene Structure of the Nerve Myoglobin of Aphrodite aculeata [PDF]
Journal of Biological Chemistry, 1996 The globin of the nerve cord of the polychaete annelid Aphrodite aculeata was isolated and purified to homogeneity. The native molecule has a pI of 6.3 and acts as a dimer of two identical Mr 15, 644.5 polypeptide chains as determined by electrospray mass spectrometry.
Dewilde, Sylvia +7 more
openaire +4 more sources
The effects of a globin blocker on the resolution of 3’mRNA sequencing data in porcine blood
BMC Genomics, 2019 Background Gene expression profiling in blood is a potential source of biomarkers to evaluate or predict phenotypic differences between pigs but is expensive and inefficient because of the high abundance of globin mRNA in porcine blood. These limitations
Kyu-Sang Lim +10 more
doaj +2 more sources
BMC Biology, 2008 Background Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin locus, the α- and β-globin clusters expanded, and then were ...
Warren Wesley C +7 more
doaj +3 more sources
Cellsβ-globin gene cluster regulation involves complex mechanisms to ensure proper expression and function in RBCs. During development, switching occurs as γ-globin is replaced by β-globin.
Alawi Habara
doaj +2 more sources
A Globin in the Nucleus! [PDF]
Journal of Biological Chemistry, 2003 Cytoglobin and neuroglobin are recently discovered members of the globin family. In situ hybridization localized neuroglobin mainly in brain and retina, while cytoglobin was expressed ubiquitously in all analyzed tissues. In the present study, polyclonal antibodies were raised against both proteins and the distribution of them was studied by ...
Geuens, Eva +5 more
openaire +3 more sources
Regulation of the Globin Genes [PDF]
Pediatric Research, 2002 The a- and b-globin gene clusters are subject to several levels of regulation. They are expressed exclusively in the erythroid cells, only during defined periods of development and in a perfectly tuned way, assuring, at any stage of ontogeny, a correct balance in the availability of a- and b-globin chains for hemoglobin assembling. Such a tight control
Cao A, MOI, PAOLO
openaire +3 more sources
TMEM8 – a non-globin gene entrapped in the globin web [PDF]
Nucleic Acids Research, 2009 For more than 30 years it was believed that globin gene domains included only genes encoding globin chains. Here we show that in chickens, the domain of alpha-globin genes also harbor the non-globin gene TMEM8. It was relocated to the vicinity of the alpha-globin cluster due to inversion of an approximately 170-kb genomic fragment.
Philonenko, Elena S. +5 more
openaire +2 more sources
Cotranslational Folding of Globin [PDF]
Journal of Biological Chemistry, 1997 Globin synthesis in a wheat germ cell-free translation system was performed in the presence of [3H]hemin and [35S]methionine to determine the minimal length of the nascent ribosome-bound globin chain capable of heme binding. Nascent polypeptides of predetermined size were synthesized on ribosomes by translation of truncated mRNA molecules.
A A, Komar +3 more
openaire +2 more sources
Analysis of β-globin chromatin micro-environment using a novel 3C variant, 4Cv [PDF]
, 2010 Copyright: © 2010 Pink et al.Higher order chromatin folding is critical to a number of developmental processes, including the regulation of gene expression.
Christopher H Eskiw +17 more
core +1 more source