Results 201 to 210 of about 8,559 (239)
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Globin X: A highly stable intrinsically hexacoordinate globin
Journal of Inorganic Biochemistry, 2022Several novel members of the vertebrate globin family were recently discovered with unique structural features that are not found in traditional penta-coordinate globins. Here we combine structural tools to better understand and recognize molecular determinants that contribute to the stability of hexacoordinate globin X (GbX) from Danio rerio ...
Rifat, Farhana +8 more
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Advances in Microbial Physiology, 2003
Globins are an ancient and diverse superfamily of proteins. The globins of microorganisms were relatively ignored for many decades after their discovery by Warburg in the 1930s and rediscovery by Keilin in the 1950s. The relatively recent focus on them has been fuelled by recognition of their structural diversity and fine-tuning to fulfill (probably ...
Guanghui Wu, Robert K Poole
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Globins are an ancient and diverse superfamily of proteins. The globins of microorganisms were relatively ignored for many decades after their discovery by Warburg in the 1930s and rediscovery by Keilin in the 1950s. The relatively recent focus on them has been fuelled by recognition of their structural diversity and fine-tuning to fulfill (probably ...
Guanghui Wu, Robert K Poole
exaly +3 more sources
The FASEB Journal, 2006
The discovery that a myoglobin‐like hemeprotein (called neuroglobin) is expressed in our brain raised considerable curiosity from the standpoints of biochemistry and pathophysiology alike. Neuroglobin is involved in neuroprotection from damage due to hypoxia or ischemia in vitro and
BRUNORI, Maurizio, VALLONE, Beatrice
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The discovery that a myoglobin‐like hemeprotein (called neuroglobin) is expressed in our brain raised considerable curiosity from the standpoints of biochemistry and pathophysiology alike. Neuroglobin is involved in neuroprotection from damage due to hypoxia or ischemia in vitro and
BRUNORI, Maurizio, VALLONE, Beatrice
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Gene, 2007
Putative globins have been identified in 426 bacterial, 32 Archaeal and 67 eukaryote genomes. Among these sequences are the hitherto unsuspected presence of single domain sensor globins within Bacteria, Fungi, and a Euryarchaeote. Bayesian phylogenetic trees suggest that their occurrence in the latter two groups could be the result of lateral gene ...
Vinogradov, Serge N. +6 more
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Putative globins have been identified in 426 bacterial, 32 Archaeal and 67 eukaryote genomes. Among these sequences are the hitherto unsuspected presence of single domain sensor globins within Bacteria, Fungi, and a Euryarchaeote. Bayesian phylogenetic trees suggest that their occurrence in the latter two groups could be the result of lateral gene ...
Vinogradov, Serge N. +6 more
openaire +3 more sources
The Globins of Campylobacter jejuni
2013Campylobacter jejuni is a zoonotic Gram-negative bacterial pathogen that is exposed to reactive nitrogen species, such as nitric oxide, from a variety of sources. To combat the toxic effects of this nitrosative stress, C. jejuni upregulates a small regulon under the control of the transcriptional activator NssR, which positively regulates the ...
Mariana, Tinajero-Trejo, Mark, Shepherd
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The Globins of Cyanobacteria and Algae
2013Approximately, 20 years ago, a haemoglobin gene was identified within the genome of the cyanobacterium Nostoc commune. Haemoglobins have now been confirmed in multiple species of photosynthetic microbes beyond N. commune, and the diversity of these proteins has recently come under increased scrutiny.
Eric A, Johnson, Juliette T J, Lecomte
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Molecular weight determinations on the α-globin and β-globin mRNAs
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976The globin mRNAs containing between 30 and 40 polyadenylate residues can be separated from thos mRNAs containing longer poly(A) regions by Millipore filter binding. The molecular weights of the alpha-and beta-globin mRNAs containing this size class of poly(A) have beed determined by lectrophoresis on 3.7% polyacrylamide gels in the presence of 99 ...
M R, Morrison, J B, Lingrel
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Activation of the δ-Globin Gene by the β-Globin Gene CACCC Motif
Blood Cells, Molecules, and Diseases, 1999The promoter region of adult beta globin genes in humans and other mammals contains conserved regions of pivotal importance for their regulated tissue specific expression. These include the CACCC and CAAT motifs. The CACCC motif is duplicated in humans and other mammals.
M. S. RISTALDI +5 more
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2013
A bioinformatics survey of about 120 protist and 240 fungal genomes and transcriptomes revealed a broad array of globins, representing five of the eight subfamilies identified in bacteria. Most conspicuous is the absence of protoglobins and globin-coupled sensors, except for a two-domain globin in Leishmanias, that comprises a nucleotidyl cyclase ...
Serge N, Vinogradov +5 more
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A bioinformatics survey of about 120 protist and 240 fungal genomes and transcriptomes revealed a broad array of globins, representing five of the eight subfamilies identified in bacteria. Most conspicuous is the absence of protoglobins and globin-coupled sensors, except for a two-domain globin in Leishmanias, that comprises a nucleotidyl cyclase ...
Serge N, Vinogradov +5 more
openaire +2 more sources
Nature, 2000
The globins are well-known proteins, and in vertebrates there are two types: haemoglobin and myoglobin. Now a third has been identified, in both mice and humans, that occurs in the nervous system, especially the brain. Like the other globins its main function is probably facilitating oxygen supply.
Luc Moens, Sylvia Dewilde, Moens Luc
exaly +2 more sources
The globins are well-known proteins, and in vertebrates there are two types: haemoglobin and myoglobin. Now a third has been identified, in both mice and humans, that occurs in the nervous system, especially the brain. Like the other globins its main function is probably facilitating oxygen supply.
Luc Moens, Sylvia Dewilde, Moens Luc
exaly +2 more sources