Results 91 to 100 of about 33,604 (226)
Central Diabetes Insipidus in Suprasellar Germ Cell Tumor Paradoxically Presenting With Oliguria
ABSTRACT Central diabetes insipidus may present as oliguric acute kidney injury (AKI), particularly in patients with communication difficulties. While polyuria is common in AKI recovery, persistent or unexplained hypernatremia should prompt suspicion for alternative diagnoses such as unmasked diabetes insipidus to ensure timely recognition and ...
Karen Kin Nam Wong +2 more
wiley +1 more source
Background/objectives: Recent data suggest a role for heparanase in several proteinuric conditions. An increased glomerular heparanase expression is associated with loss of heparan sulfate in the glomerular basement membrane (GBM). The aim of the present
Roshan-Milani S. +2 more
doaj +1 more source
The essential function of the kidney is to ensure formation of relatively protein-free ultra-filtrate, urine. The rate of filtration and composition of the primary renal filtrate is determined by the transport of fluid and solutes across the glomerular ...
Ram K Menon +3 more
doaj +1 more source
On the measurement of glomerular filtration rate: An odyssey into the milieu intérieur
Experimental Physiology, EarlyView.
Anders Møller Greve +4 more
wiley +1 more source
ALKBH5‐modified UC‐MSCs‐derived exosomes (OE‐ALKBH5 Exo) inhibit the expression of M1 markers (iNOS, IL‐1β, TNF‐α, CD86) and enhance the expression of M2 markers (IL‐10, Arg‐1, CD206) by inhibiting the m6A methylation of TRAF6 and reducing its protein level and stability, thereby promoting M2 polarisation and alleviating the progression of DKD ...
Lei Li +5 more
wiley +1 more source
A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier
The glomerular filtration barrier is a complex structure in charge of renal ultrafiltration. Here the authors present a glomerulus-on-a-chip for disease modelling and high-throughput drug screening where human podocytes and human glomerular endothelial ...
Astgik Petrosyan +8 more
doaj +1 more source
Characterization of human anti-glomerular basement membrane antibodies eluted from glomerulonephritic kidneys [PDF]
John J. McPhaul, Frank J. Dixon
openalex +1 more source
ABSTRACT Ulcerative colitis (UC) is a chronic intestinal inflammatory disease with complex pathogenesis. Previous studies have shown that probiotics alleviate UC by modulating the gut microbiome. Therefore, this study aimed to investigate the ameliorative effect of Lactobacillus plantarum 6C (L.
Jiashan Qin +6 more
wiley +1 more source
Disulfiram is widely applied for treating chronic alcoholism. In recent years, researchers have proposed specific anti-cancer mechanisms by disulfiram, such as arresting the activity of acetaldehyde dehydrogenase (ALDH) and boosting intracellular ...
Yan-yu Zhang +5 more
doaj +1 more source
ABSTRACT Dietary soluble fiber may alleviate renal damage in chronic kidney disease (CKD) by promoting intestinal urea excretion, though the underlying mechanisms remain unclear. This study investigated the digestion, fermentation, and renoprotective effects of Coix lachryma‐jobi L.
Hongmei Yin +9 more
wiley +1 more source

