Results 111 to 120 of about 107,331 (315)
Journal of Small Animal Practice, EarlyView.Objectives To evaluate the glomerular ultrastructural changes associated with diabetic nephropathy and quantify glomerular vascular endothelial growth factor‐A expression in cats with diabetes mellitus compared to controls. Materials and Methods Transmission electron microscopy was performed to evaluate glomerular ultrastructural changes, including ...
H. Reyes‐Hughes +6 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2020 病例资料患者,男,38岁,因"痰中带血1个月"于2018年7月12日入院。入院前1个月,患者无明显诱因出现暗红色血痰,量少,咳2～3口,不伴有发热、胸闷、气紧,于2018年6月7日到广元市人民医院门诊就诊,查胸部CT示双肺多发渗出灶,未予以处理。此后患者未再出现痰中带血 ...
HAO Yu, QIN Wei
doaj
TGF-beta 1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy [PDF]
, 2010 Background/Aims: Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis.
Hills, Claire E., Squires, Paul E.
core +1 more source
Experimental Biology and Medicine, 1966 SummaryA method has been described for obtaining isolated human glomerular basement membrane. Evidence for the purity of the isolated GBM includes electron microscopic and chemical data. Some of the membrane constituents, in particular hydroxypro-line, aminosugars, sialic acid, neutral sugars, and lipids have been identified.
R. P. Misra, L. B. Berman
openaire +3 more sources
PLoS ONE, 2011 The filtering unit of the kidney, the glomerulus, contains capillaries whose walls function as a biological sieve, the glomerular filtration barrier.
Sadie C. Slater +9 more
semanticscholar +1 more source
Basement Membrane Defects in Genetic Kidney Diseases
Frontiers in Pediatrics, 2018 The glomerular basement membrane (GBM) is a specialized structure with a significant role in maintaining the glomerular filtration barrier. This GBM is formed from the fusion of two basement membranes during development and its function in the filtration
C. Chew, R. Lennon
semanticscholar +1 more source
Kidney Medicine, 2019 Alport syndrome is a hereditary glomerular nephritis associated with hearing loss and eye abnormalities and is classified as X-linked Alport syndrome, autosomal recessive Alport syndrome, and autosomal dominant Alport syndrome.
Taro Akihisa +12 more
doaj
Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis. [PDF]
, 2000 Protease-activated receptor (PAR)-1 is a cellular receptor for thrombin that is activated after proteolytic cleavage. The contribution of PAR-1 to inflammatory cell-mediated renal injury was assessed in murine crescentic glomerulonephritis (GN).
Bernatowicz +33 more
core +3 more sources
Glomerular basement membrane disorders and the kidney
Medicine, 2011 The glomerular basement membrane (GBM) is the vital barrier between blood and glomerular filtrate. Diseases that damage it generally cause haematuria initially, but as architecture becomes disordered proteinuria becomes an increasing feature. Inflammatory glomerulonephritis most commonly does this, but genetic abnormalities of GBM components are ...
A Neil Turner, Eleri Williams
openaire +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic +9 more
wiley +1 more source