Results 11 to 20 of about 33,604 (226)

Anti-Glomerular Basement Membrane Disease in a 10-year-old Child: A Case Report

open access: yesJournal of Nepal Medical Association, 2023
Anti-glomerular basement membrane disease is an extremely uncommon entity in children. It has an incidence of 0.5 to 1 per million per year in adults and is even more uncommon in children.
Md Firoz Anjum   +4 more
doaj   +1 more source

Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report

open access: yesSAGE Open Medical Case Reports, 2023
Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh   +3 more
doaj   +1 more source

Molecular and Cellular Mechanisms Underlying the Initiation and Progression of Alport Glomerular Pathology

open access: yesFrontiers in Medicine, 2022
Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)2α2(IV)1 heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a ...
Dominic Cosgrove, Jacob Madison
doaj   +1 more source

Antiglomerular Basement Membrane Disease [PDF]

open access: yesSeminars in Respiratory and Critical Care Medicine, 2014
AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
openaire   +7 more sources

Tubular basement membrane deposits after allogeneic hematopoietic stem cell transplantation

open access: yesBMC Nephrology, 2023
Background Extraglomerular immune complex deposition is rare and only a few membranous nephropathy cases with tubular basement membrane deposits have been reported following allogeneic hematopoietic stem cell transplantation.
Wenyan Zhou   +4 more
doaj   +1 more source

Etanercept-Induced Anti-Glomerular Basement Membrane Disease

open access: yesCase Reports in Nephrology and Dialysis, 2021
Anti-glomerular basement membrane (anti-GBM) disease is a rare form of small-vessel vasculitis that typically causes rapidly progressive glomerulonephritis with or without alveolar haemorrhage.
Saif Al-Chalabi   +3 more
doaj   +1 more source

Anti-glomerular basement membrane disease [PDF]

open access: yesKidney International, 2003
Human anti-glomerular basement membrane (anti-GBM) disease is a rare disorder characterized by rapidly progressive glomerulonephritis (RPGN) and lung haemorrhage. However, it is the cause of only about one third of the cases of this clinical syndrome, and lung haemorrhage does not occur in all patients.
Pusey, CD   +13 more
openaire   +3 more sources

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Mechanisms of Podocyte Detachment, Podocyturia, and Risk of Progression of Glomerulopathies

open access: yesKidney Diseases, 2020
Background: Glomerulopathies are the main cause of ESRD. Primary or secondary causes of glomerular diseases comprise more than 70% of cases that end up in renal replacement therapies.
Hernán Trimarchi
doaj   +1 more source

Anti-Glomerular Basement Membrane Disease [PDF]

open access: yesJournal of the American Society of Nephrology, 1999
Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement membrane.
D C, Kluth, A J, Rees
openaire   +2 more sources

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