Results 21 to 30 of about 107,331 (315)
THE ROLE OF ANTI-GLOMERULAR BASEMENT MEMBRANE ANTIBODY IN THE PATHOGENESIS OF HUMAN GLOMERULONEPHRITIS [PDF]
Journal of Experimental Medicine, 1967 These observations established the presence of anti-GBM antibodies in the sera and/or kidneys of six humans with glomerulonephritis. Further, it seems clear that these antibodies do combine with the host's glomeruli in vivo and with GBM antigen of ...
Richard A. Lerner +2 more
openalex +2 more sources
Goodpasture syndrome and anti-glomerular basement membrane disease.
Clinical and Experimental Rheumatology, 2023 Anti-glomerular basement membrane (anti-GBM) disease is a rare life-threatening small vessel vasculitis that typically affects the capillaries of kidneys and lungs, with most of patients developing rapidly progressive crescentic glomerulonephritis, and ...
F. Reggiani +4 more
semanticscholar +1 more source
Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
doaj +1 more source
Frontiers in Medicine, 2022 Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)2α2(IV)1 heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a ...
Dominic Cosgrove, Jacob Madison
doaj +1 more source
Diagnosis of Glomerular Disease With Podocyte Infolding, Microspherical, and Microtubular Glomerular Basement Membrane Inclusions [PDF]
Kidney International Reports, 2023 Satoru Kudose, M. Barry Stokes
doaj +2 more sources
Anti-Glomerular Basement Membrane Disease
Definitions, 2020 Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement ...
A. Rees
semanticscholar +1 more source
Etanercept-Induced Anti-Glomerular Basement Membrane Disease
Case Reports in Nephrology and Dialysis, 2021 Anti-glomerular basement membrane (anti-GBM) disease is a rare form of small-vessel vasculitis that typically causes rapidly progressive glomerulonephritis with or without alveolar haemorrhage.
Saif Al-Chalabi +3 more
doaj +1 more source
Tubular basement membrane deposits after allogeneic hematopoietic stem cell transplantation
BMC Nephrology, 2023 Background Extraglomerular immune complex deposition is rare and only a few membranous nephropathy cases with tubular basement membrane deposits have been reported following allogeneic hematopoietic stem cell transplantation.
Wenyan Zhou +4 more
doaj +1 more source
Clinical Kidney Journal, 2020 Background Patients heterozygous for COL4A3 or COL4A4 mutations show a wide spectrum of disease, extending from familial isolated microscopic haematuria, as a result of thin basement membranes (TBMs), to autosomal dominant Alport syndrome (ADAS) and end ...
Andreas M. Matthaiou +2 more
semanticscholar +1 more source
Anti-glomerular basement membrane disease [PDF]
Kidney International, 2003 Human anti-glomerular basement membrane (anti-GBM) disease is a rare disorder characterized by rapidly progressive glomerulonephritis (RPGN) and lung haemorrhage. However, it is the cause of only about one third of the cases of this clinical syndrome, and lung haemorrhage does not occur in all patients.
Pusey, CD +13 more
openaire +4 more sources