Results 21 to 30 of about 33,604 (226)

Anti-glomerular basement membrane disease superimposed on membranous nephropathy: a case report and review of the literature

Journal of Medical Case Reports, 2010
Introduction Anti-glomerular basement membrane disease is a rare autoimmune disorder characterized by pulmonary hemorrhage, crescentic glomerulonephritis and the presence of circulating anti-glomerular basement membrane antibodies.
Nivera Noel, Patel Dhruval, Tunkel Allan R   +2 more
doaj   +1 more source

Anti-glomerular basement membrane glomerulonephritis following nintedanib for idiopathic pulmonary fibrosis: a case report

Journal of Medical Case Reports, 2017
Background We report a previously unrecognized and unreported case of a patient with anti-glomerular basement membrane glomerulonephritis following nintedanib, an orally active small molecule tyrosine kinase inhibitor.
Ibrahim Ismail, Sonu Nigam, Alan Parnham, Vinay Srinivasa   +3 more
doaj   +1 more source

Glomerular basement membrane and related glomerular disease [PDF]

Translational Research, 2012
The glomerular basement membrane (GBM) is lined by fenestrated endothelium from the capillary-lumen side and by interdigitating foot processes of the podocytes from the urinary- space side. These three layers of the glomerular capillary wall constitute the functional unit of the glomerular filtration barrier.
Ying Maggie, Chen, Jeffrey H, Miner
openaire   +2 more sources

Anti–Glomerular Basement Membrane Disease

Rheumatic Disease Clinics of North America, 2018
Anti-glomerular basement membrane (anti-GBM) disease is a rare autoimmune small vessel vasculitis characterized by autoreactivity to antigens in type IV collagen chains expressed in glomerular and alveolar basement membrane. The detection of circulating anti-GBM antibodies, which are shown to be directly pathogenic, is central to disease diagnosis ...
Gulati, K, McAdoo, SP
openaire   +4 more sources

The Mayo Clinic consensus report on membranous nephropathy; a promising step toward better treating the disease [PDF]

Journal of Nephropharmacology
Membranous nephropathy is an immune complex disease caused by subepithelial deposits. The pathological manifestations of membranous nephropathy are considered by the creation of immune complexes in the epithelial cells of the glomerular basement membrane.
Samaneh Zandifar, Leila Alem, Azadeh Khayyat, Mohammad Ali Esmaeil Pour   +3 more
doaj   +1 more source

Anti-glomerular Basement Membrane Disease with Atypical Associations

Saudi Journal of Kidney Diseases and Transplantation, 2021
Anti-glomerular basement membrane (anti-GBM) disease is a systemic autoimmune disorder characterized by circulating immunoglobulin (Ig) G antibodies to carboxy-terminal, noncollagenous 1 domain of type IV collagen of GBM.
Prashant Bharat Malviya, Somashekhar Modigonda, Sanjay Maitra, Swarnalata Gowrishankar   +3 more
doaj   +1 more source

Complexities of the glomerular basement membrane [PDF]

Nature Reviews Nephrology, 2020
The glomerular basement membrane (GBM) is a key component of the glomerular capillary wall and is essential for kidney filtration. The major components of the GBM include laminins, type IV collagen, nidogens and heparan sulfate proteoglycans. In addition, the GBM harbours a number of other structural and regulatory components and provides a reservoir ...
Richard W. Naylor, Mychel R. P. T. Morais, Rachel Lennon   +2 more
openaire   +2 more sources

SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report

BMC Nephrology, 2021
Background Anti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage.
Alexander Winkler, Emanuel Zitt, Hannelore Sprenger-Mähr, Afschin Soleiman, Manfred Cejna, Karl Lhotta   +5 more
doaj   +1 more source

An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement

Respiratory Medicine Case Reports, 2020
Anti-glomerular basement membrane disease (anti-GBM) is a well-documented, small vessel vasculitis that is classically associated with glomerulonephritis and alveolitis [1].
Jeremy Polman, Rory Panzarello, Pratik Patel, Vasudev Tati   +3 more
doaj   +1 more source

Case report: A case report of Alport syndrome caused by a novel mutation of COL4A5

Frontiers in Genetics, 2023
Alport syndrome (#308940) is an X-linked genetic disease with clinical manifestations, such as hematuria, proteinuria, renal insufficiency, and end-stage renal disease.
Shujun Pan, Rizhen Yu, Shikai Liang
doaj   +1 more source