Results 41 to 50 of about 108,933 (325)

Anti-glomerular basement membrane glomerulonephritis following nintedanib for idiopathic pulmonary fibrosis: a case report

Journal of Medical Case Reports, 2017
Background We report a previously unrecognized and unreported case of a patient with anti-glomerular basement membrane glomerulonephritis following nintedanib, an orally active small molecule tyrosine kinase inhibitor.
Ibrahim Ismail, Sonu Nigam, Alan Parnham, Vinay Srinivasa   +3 more
doaj   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Anti-glomerular Basement Membrane Disease with Atypical Associations

Saudi Journal of Kidney Diseases and Transplantation, 2021
Anti-glomerular basement membrane (anti-GBM) disease is a systemic autoimmune disorder characterized by circulating immunoglobulin (Ig) G antibodies to carboxy-terminal, noncollagenous 1 domain of type IV collagen of GBM.
Prashant Bharat Malviya, Somashekhar Modigonda, Sanjay Maitra, Swarnalata Gowrishankar   +3 more
doaj   +1 more source

Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. [PDF]

, 2006
BackgroundGlomerular basement membrane (GBM), a key component of the blood-filtration apparatus in the in the kidney, is formed through assembly of type IV collagen with laminins, nidogen, and sulfated proteoglycans.
Cosgrove, Dominic, Kalluri, Raghu, Khurana, Mona, Rao, Velidi H, Rougier, Jean-Philippe, Shield, Charles F, Werb, Zena, Werner, Michelle C, Zeisberg, Michael   +8 more
core   +3 more sources

The Mayo Clinic consensus report on membranous nephropathy; a promising step toward better treating the disease [PDF]

Journal of Nephropharmacology
Membranous nephropathy is an immune complex disease caused by subepithelial deposits. The pathological manifestations of membranous nephropathy are considered by the creation of immune complexes in the epithelial cells of the glomerular basement membrane.
Samaneh Zandifar, Leila Alem, Azadeh Khayyat, Mohammad Ali Esmaeil Pour   +3 more
doaj   +1 more source

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.

Journal of the American Society of Nephrology, 2019
BACKGROUND Although diabetic kidney disease demonstrates both familial clustering and single nucleotide polymorphism heritability, the specific genetic factors influencing risk remain largely unknown.
R. M. Salem, Jennifer N. Todd, N. Sandholm, J. Cole, Wei-Min Chen, D. Andrews, M. Pezzolesi, P. McKeigue, Linda T. Hiraki, Chengxiang Qiu, V. Nair, Chen Di Liao, Jing Jing Cao, E. Valo, Suna Onengut-Gumuscu, A. Smiles, S. McGurnaghan, Jani K. Haukka, V. Harjutsalo, E. Brennan, N. Zuydam, E. Ahlqvist, Ross Doyle, T. Ahluwalia, M. Lajer, Maria Hughes, Jihwan Park, J. Skupień, A. Spiliopoulou, Andrew Liu, R. Menon, Carine M. Boustany-Kari, Hyun Min Kang, R. Nelson, R. Klein, B. E. Klein, Kristine E. Lee, Xiaoyu Gao, M. Mauer, S. Maestroni, M. L. Caramori, Ian H. de Boer, Rachel G Miller, J. Guo, A. Boright, D. Trégouët, B. Gyorgy, J. Snell-Bergeon, D. Maahs, Shelley B. Bull, A. J. Canty, C. N. Palmer, L. Stechemesser, B. Paulweber, R. Weitgasser, J. Sokolovska, V. Rovite, V. Pirags, E. Prakapienė, L. Radzeviciene, R. Verkauskienė, N. Panduru, L. Groop, M. McCarthy, H. Gu, A. Möllsten, H. Falhammar, K. Brismar, F. Martin, P. Rossing, T. Costacou, G. Zerbini, M. Marre, S. Hadjadj, A. McKnight, C. Forsblom, G. Mckay, C. Godson, A. P. Maxwell, M. Kretzler, K. Suszták, H. Colhoun, A. Krolewski, Andrew D. Paterson, P. Groop, S. Rich, J. Hirschhorn, J. C. Florez   +87 more
semanticscholar   +1 more source

Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]

, 2014
Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core   +6 more sources

SARS-CoV-2 infection and recurrence of anti-glomerular basement disease: a case report

BMC Nephrology, 2021
Background Anti-glomerular basement membrane disease (GBM) disease is a rare autoimmune disease causing rapidly progressive glomerulonephritis and pulmonary haemorrhage.
Alexander Winkler, Emanuel Zitt, Hannelore Sprenger-Mähr, Afschin Soleiman, Manfred Cejna, Karl Lhotta   +5 more
doaj   +1 more source

Anti-Glomerular Basement Membrane Disease.

American Society of Nephrology. Clinical Journal, 2017
Anti-glomerular basement membrane (anti-GBM) disease is a rare small vessel vasculitis that affects the capillary beds of the kidneys and lungs. It is an archetypic autoimmune disease, caused by the development of directly pathogenic autoantibodies ...
S. McAdoo, C. Pusey
semanticscholar   +1 more source

Antiglomerular Basement Membrane Disease [PDF]

Seminars in Respiratory and Critical Care Medicine, 2014
AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
openaire   +9 more sources