Results 41 to 50 of about 107,331 (315)
Permselectivity of the glomerular wall examined with iron compound tracer [PDF]
, 1977 Rat kidney endothelial cell morphology was examined after introducing iron colloid particles of positive or negative charge to investigate the relationship between the electric charge and permeation through the glomerular capillary.
Hirata, Kooiti
core +1 more source
Case report: A case report of Alport syndrome caused by a novel mutation of COL4A5
Frontiers in Genetics, 2023 Alport syndrome (#308940) is an X-linked genetic disease with clinical manifestations, such as hematuria, proteinuria, renal insufficiency, and end-stage renal disease.
Shujun Pan, Rizhen Yu, Shikai Liang
doaj +1 more source
Antiglomerular Basement Membrane Disease [PDF]
Seminars in Respiratory and Critical Care Medicine, 2014 AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
openaire +9 more sources
Anti-Glomerular Basement Membrane Disease.
American Society of Nephrology. Clinical Journal, 2017 Anti-glomerular basement membrane (anti-GBM) disease is a rare small vessel vasculitis that affects the capillary beds of the kidneys and lungs. It is an archetypic autoimmune disease, caused by the development of directly pathogenic autoantibodies ...
S. McAdoo, C. Pusey
semanticscholar +1 more source
What is new in the management of rapidly progressive glomerulonephritis? [PDF]
, 2015 Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB, Salama, AD
core +1 more source
Anti-glomerular basement membrane disease: an update on subgroups, pathogenesis and therapies.
Nephrology, Dialysis and Transplantation, 2018 Most patients with anti-glomerular basement membrane (anti-GBM) disease present with rapidly progressive glomerulonephritis with or without pulmonary haemorrhage; however, there are several variants and vigilance is necessary to make a correct diagnosis.
M. Segelmark, T. Hellmark
semanticscholar +1 more source
Acta Clinica Croatica, 2021 Aim. To investigate morphological findings of zero-time biopsies analyzed at the Department of Nephropathology and Electron Microscopy, Dubrava University Hospital, Zagreb. Materials and methods.
Petar Šenjug +7 more
doaj +1 more source
Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance Human kidneys contain ∼2 x 106 glomeruli that produce ∼180 L per day of primary filtrate. Downstream tubules reabsorb most of the water, salt, and desirable low-molecular weight substances, leaving 1 to 2 L per day of urine containing ...
Marlon G. Lawrence +10 more
semanticscholar +1 more source
Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes. [PDF]
PLoS ONE, 2013 BackgroundPodocytes serve as an important constituent of the glomerular filtration barrier. Recently, we and others identified Myo1e as a key molecular component of the podocyte cytoskeleton.ResultsMyo1e mRNA and protein was expressed in human and mouse ...
Jianhua Mao +14 more
doaj +1 more source
Rethinking glomerular basement membrane thickening in diabetic nephropathy: adaptive or pathogenic?
AJP - Renal Physiology, 2016 Diabetic nephropathy (DN) is the leading cause of chronic kidney disease in the United States and is a major cause of cardiovascular disease and death.
C. B. Marshall
semanticscholar +1 more source