Results 51 to 60 of about 107,331 (315)
Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. [PDF]
BackgroundGlomerular basement membrane (GBM), a key component of the blood-filtration apparatus in the in the kidney, is formed through assembly of type IV collagen with laminins, nidogen, and sulfated proteoglycans.
Cosgrove, Dominic+8 more
core +3 more sources
Thin glomerular basement membrane disease [PDF]
Isolated microscopic hematuria that begins in childhood and is of glomerular origin has a rather limited differential diagnosis, with Alport syndrome, IgA nephropathy, and benign familial hematuria as the most prevalent conditions. In a series of 322 children with persistent hematuria for longer than 6 months, biopsies were classified as IgA ...
openaire +3 more sources
Glomerulonephritis associated with systemic sclerosis: a case report
Background Systemic sclerosis is a multiorgan autoimmune disease that can overlap with other rheumatologic disorders; however, co-occurrence with antineutrophil cytoplasmic antibody-associated vasculitis is rare.
Sepehr Nayebirad+6 more
doaj +1 more source
The Bi-Functional Organization of Human Basement Membranes [PDF]
The current basement membrane (BM) model proposes a single-layered extracellular matrix (ECM) sheet that is predominantly composed of laminins, collagen IVs and proteoglycans.
Balasubramani, Manimalha+9 more
core +5 more sources
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides is an important cause of rapidly progressive glomerulonephritides (RPGN), and they are classically described as pauci-immune diseases as evidenced by the absence of immune deposits on ...
Wiroon Sangsiraprapha+2 more
doaj +1 more source
IgG subclass deposition in diabetic nephropathy
Purpose This study aimed to analyze the distribution of IgG subclass in diabetic nephropathy (DN) and its association with clinicopathological features.
Xuanli Tang+5 more
doaj +1 more source
Three-dimensional electron microscopy reveals the evolution of glomerular barrier injury [PDF]
Open access articleGlomeruli are highly sophisticated filters and glomerular disease is the leading cause of kidney failure. Morphological change in glomerular podocytes and the underlying basement membrane are frequently observed in disease ...
Collinson, S.+10 more
core +3 more sources
Glomerular Basement Membrane Changes in Hereditary Glomerular Diseases
Ultrastructural glomerular basement membrane changes are present in most hereditary glomerular diseases: thick and thin basement membrane with splitting of the lamina densa in Alport’s syndrome, thin basement membrane in familial benign essential hematuria, and thick basement membrane with the presence of collagen-like fibrils in the nail-patella ...
Gubler Mc, R Habib, C Naizot, M Levy
openaire +4 more sources
Membranous nephropathy is a common cause of nephrotic syndrome in adults and can be primary or secondary through autoimmune disease, medication, infection, or malignancy.
Claudius Speer+5 more
doaj +1 more source
A new outlook towards kidney injuries [PDF]
Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Abhijeet Satwekar, Mahesh Satwekar
core +2 more sources