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Anti-glomerular basement membrane disease: an update on subgroups, pathogenesis and therapies.
Nephrology, Dialysis and Transplantation, 2018 Most patients with anti-glomerular basement membrane (anti-GBM) disease present with rapidly progressive glomerulonephritis with or without pulmonary haemorrhage; however, there are several variants and vigilance is necessary to make a correct diagnosis.
M. Segelmark, T. Hellmark
semanticscholar +1 more source
A new outlook towards kidney injuries [PDF]
, 2012 Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Abhijeet Satwekar, Mahesh Satwekar
core +2 more sources
Respiratory Medicine Case Reports, 2020 Anti-glomerular basement membrane disease (anti-GBM) is a well-documented, small vessel vasculitis that is classically associated with glomerulonephritis and alveolitis [1].
Jeremy Polman +3 more
doaj +1 more source
Case report: A case report of Alport syndrome caused by a novel mutation of COL4A5
Frontiers in Genetics, 2023 Alport syndrome (#308940) is an X-linked genetic disease with clinical manifestations, such as hematuria, proteinuria, renal insufficiency, and end-stage renal disease.
Shujun Pan, Rizhen Yu, Shikai Liang
doaj +1 more source
Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance Human kidneys contain ∼2 x 106 glomeruli that produce ∼180 L per day of primary filtrate. Downstream tubules reabsorb most of the water, salt, and desirable low-molecular weight substances, leaving 1 to 2 L per day of urine containing ...
Marlon G. Lawrence +10 more
semanticscholar +1 more source
Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects [PDF]
, 2007 Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection.
Braun, Gerald S. +4 more
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Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes. [PDF]
PLoS ONE, 2013 BackgroundPodocytes serve as an important constituent of the glomerular filtration barrier. Recently, we and others identified Myo1e as a key molecular component of the podocyte cytoskeleton.ResultsMyo1e mRNA and protein was expressed in human and mouse ...
Jianhua Mao +14 more
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Thin glomerular basement membrane disease [PDF]
Kidney International, 2001 Isolated microscopic hematuria that begins in childhood and is of glomerular origin has a rather limited differential diagnosis, with Alport syndrome, IgA nephropathy, and benign familial hematuria as the most prevalent conditions. In a series of 322 children with persistent hematuria for longer than 6 months, biopsies were classified as IgA ...
openaire +3 more sources
Acta Clinica Croatica, 2021 Aim. To investigate morphological findings of zero-time biopsies analyzed at the Department of Nephropathology and Electron Microscopy, Dubrava University Hospital, Zagreb. Materials and methods.
Petar Šenjug +7 more
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Immunofluorescent Examination of Biopsies from Long-Term Renal Allografts [PDF]
, 1970 Immunofluorescent examination of open renal biopsies revealed clear-cut glomerular localization of immunoglobulins not related clearly to the quality of donor-recipient histocompatibility in 19 of 34 renal allografts.
Busch +9 more
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