Results 111 to 120 of about 40,034 (308)

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

Advanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li, Shimin Jiang, Qi Jin, Peng Qu, Yingjie Guo, Xushan Lan, Xinyu Li, Cuiting Sun, Sinan Ai, Xin Li, Weiliang Sun, Jing Guo, Wenge Li, Liang Peng, Lihong Liu   +14 more
wiley   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

The glomerulus reveals some secrets

, 2015
Agnes B. Fogo
openalex   +2 more sources

Cyclin and cyclin-dependent kinase expression in the remnant glomerulus. [PDF]

, 1997
Stuart J. Shankland, Paul A. Hamel, J. W. Scholey   +2 more
openalex   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

Effectiveness of white guava leaves (Psidium guajava var. Pyrifera l.) In repair proximal tubule damage and glomerulus diameter in hyperglycemic mice

, 2023
Eko Naning Sofyanita, Anisa Rizky Yunianti   +1 more
openalex   +2 more sources

The Evolution of Gas Sensors Into Neuromorphic Systems

Advanced Electronic Materials, EarlyView.
Gas sensors are vital for various applications, but conventional designs rely on separate sensing, memory, and processing units, limiting speed, power efficiency, and adaptability. Neuromorphic gas sensing overcomes these constraints by integrating all functions in a single device.
Kevin Dominguez, Dhananjay D. Kumbhar, Abdul Momin Syed, Regina C. Martin, Nazek El‐Atab   +4 more
wiley   +1 more source

Ketorolak Intravena dan Laju Filtrasi Glomerulus pada Anestesi Isofluran

, 2010
Rosa Afriani, Heru Dwi Jatmiko
openalex   +1 more source

PD33-01 GLOMERULUS ON-A-CHIP AS A MODEL TO STUDY THE GLOMERULAR FILTRATION BARRIER IN VITRO [PDF]

, 2018
Stefano Da Sacco, Paul Vulto, Jos Joore, Roger De Filippo, Laura Perin   +4 more
openalex   +1 more source

The biology of the glomerulus: Endothelial cells

Kidney International, 1994
Endothelial cells are active participants in processes controlling coagulation, inflammation and immune processes and an aberration in the controlling mechanisms may contribute to the development of disease within the glomerulus. The major goal of the next few years will be to develop reliable and reproducible methods for isolation and culture of ...
openaire   +2 more sources