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The cellular history of the glomerulus
Journal of Nephrology, 2003Abstract Knowledge about the structure and functions of the cells of the glomeruli has accumulated slowly over the past 350 years. Marcello Malpighi originated the work, but it failed to progress far until Schleiden and Schwann developed their cellular theory in 1839.
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Transplantation, 2017
Organ-on-chip is an emerging technology for drug testing, disease modelling, and organ function modeling. Despite development of nephron-on-chip1 and its components, such as proximal-tubule-on-chip,2 glomerulus-on-chip has not been realized mostly due to lack of functional podocytes.
Ashammakhi, Nureddin +2 more
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Organ-on-chip is an emerging technology for drug testing, disease modelling, and organ function modeling. Despite development of nephron-on-chip1 and its components, such as proximal-tubule-on-chip,2 glomerulus-on-chip has not been realized mostly due to lack of functional podocytes.
Ashammakhi, Nureddin +2 more
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Effects of aging on the renal glomerulus
The American Journal of Medicine, 1986The biologic price of aging includes progressive deterioration of renal function and structure. After the age of 30, glomerular filtration and renal blood flow rates decline in a linear fashion, so that values in octagenarians are only half to two thirds those measured in young adults.
S, Anderson, B M, Brenner
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2015
Abstract The glomerulus performs its functions with three major cell types. Endothelial cells and visceral epithelial cells (podocytes) lie on the inside and outside of the glomerular basement membrane, and together these three structures form the glomerular filtration barrier. Mesangial cells sit in the axial region.
Marlies Elger, Wilhelm Kriz
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Abstract The glomerulus performs its functions with three major cell types. Endothelial cells and visceral epithelial cells (podocytes) lie on the inside and outside of the glomerular basement membrane, and together these three structures form the glomerular filtration barrier. Mesangial cells sit in the axial region.
Marlies Elger, Wilhelm Kriz
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2015
The glomeruli of kidney are selective filtering corpuscles composed of a capillary network, podocytes, and mesangial cells (panel a). The glomerular basement membrane (GBM) is situated between capillary endothelia and podocytes (cf. Fig. 107). All three cell types and the GBM are important for the ultrafiltration of plasma.
Margit Pavelka, Jürgen Roth
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The glomeruli of kidney are selective filtering corpuscles composed of a capillary network, podocytes, and mesangial cells (panel a). The glomerular basement membrane (GBM) is situated between capillary endothelia and podocytes (cf. Fig. 107). All three cell types and the GBM are important for the ultrafiltration of plasma.
Margit Pavelka, Jürgen Roth
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Seminars in nephrology, 1996
Glomerular filtration rate (GFR) decreases with advancing age, particularly in men, although the rate of decrease in GFR is highly variable. Renal vasoconstriction contributes to the decrease in GFR because of increased renal nerve activity, angiotensin II, endothelin, and decreases in vasodilatory prostacyclin levels.
C, Baylis, R, Schmidt
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Glomerular filtration rate (GFR) decreases with advancing age, particularly in men, although the rate of decrease in GFR is highly variable. Renal vasoconstriction contributes to the decrease in GFR because of increased renal nerve activity, angiotensin II, endothelin, and decreases in vasodilatory prostacyclin levels.
C, Baylis, R, Schmidt
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A Personalized Glomerulus Chip Engineered from Stem Cell-Derived Epithelium and Vascular Endothelium
Micromachines, 2021Yasmin Roye +2 more
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