Results 111 to 120 of about 48,150 (297)

Allium sativum, a Natural and Pharmaco‐Remedial Panacea for Entero‐Gastritis, Antibiocidal/Dysbiogenesis, and Systemic Health Relevance

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Natural Pharmaco‐remedial impacts of Allium sativum on Systemic health. ABSTRACT Arising from the emergence of diverse difficult‐to‐treat health cases, alterative‐therapeutic strategies have become a potential way forward for management/control. In traditional Chinese medicine (TCM), various plant materials have been sourced as alterative‐therapeutic ...
Patience O. Adomi, Bright E. Igere, Anthony J. Anozie, Oghenenyore A. Ohwokevwo   +3 more
wiley   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

A disease model of diabetic nephropathy in a glomerulus-on-a-chip microdevice

, 2017
A biomimetic glomerulus-on-a-chip microdevice was created to recapitulate a disease model of diabetic nephropathy.
Hao Yu, Wentao Su, Li Wang, Tingting Tao, Yue Yu, Jianhua Qin   +5 more
core   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Glomerulus-on-a-Chip: Current Insights and Future Potential Towards Recapitulating Selectively Permeable Filtration Systems

International Journal of Nephrology and Renovascular Disease, 2022
Kotaro Doi,1 Hiroshi Kimura,2 Yukiko T Matsunaga,1 Teruo Fujii,3 Masaomi Nangaku4 1Institute of Industrial Science, The University of Tokyo, Tokyo, Japan; 2Department of Mechanical Engineering, School of Engineering, Tokai University, Kanagawa, Japan ...
Doi K, Kimura H, Matsunaga YT, Fujii T, Nangaku M   +4 more
doaj  

The Presence and Percentage of Circulating Nucleated Red Blood Cells Reveal Distinct Characteristics in Adults With Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT Although circulating nucleated red blood cells (cNRBCs) have previously been detected in patients with sickle cell disease (SCD), their prevalence and clinical significance during steady‐state disease have not been established. We retrospectively analyzed 270 adults with an SS or Sβ0‐thalassemia genotype.
Ugo Boccadifuoco, Ivan Lerner, Auria Godard, Luc Darnige, Laure Joseph, Wassim El Nemer, Geoffrey Cheminet, Jean‐Benoit Arlet   +7 more
wiley   +1 more source

Association of high vibration perception threshold with reduced renal function in patients with type 2 diabetes

Frontiers in Endocrinology
ObjectiveTo investigate the correlation between vibration sensory threshold (VPT) and renal function, including glomerulus and renal tubule, in patients with type 2 diabetes mellitus (T2DM).MethodsA total of 1274 patients with T2DM who were enrolled in ...
Yongze Zhang, Yongze Zhang, Yongze Zhang, Yongze Zhang, Yongze Zhang, Yongze Zhang, Biao Zheng, Biao Zheng, Biao Zheng, Biao Zheng, Biao Zheng, Biao Zheng, Yimei Li, Yimei Li, Yimei Li, Yimei Li, Yimei Li, Yimei Li, Ximei Shen, Ximei Shen, Ximei Shen, Ximei Shen, Ximei Shen, Ximei Shen, Lingning Huang, Lingning Huang, Lingning Huang, Lingning Huang, Lingning Huang, Lingning Huang, Fengying Zhao, Fengying Zhao, Fengying Zhao, Fengying Zhao, Fengying Zhao, Fengying Zhao, Sunjie Yan, Sunjie Yan, Sunjie Yan, Sunjie Yan, Sunjie Yan, Sunjie Yan   +41 more
doaj   +1 more source

Pengaruh Ekstrak Kulit Tomat terhadap Luas Glomerulus Ginjal Tikus Model Diabetes Melitus Tipe 2 [PDF]

, 2017
Diabetes melitus (DM) tipe 2 merupakan penyakit metabolik yang terjadi karena defek progresif dari sekresi insulin yang didasari oleh resistensi insulin.
Hapsari, Prahita Atyan
core  

Construction Trade Work Is Associated With Accelerated Decline in Kidney Function

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Construction workers are exposed to airborne particulates, organic solvents, and metals—agents linked to elevated risk of chronic kidney disease (CKD). Few studies have evaluated whether construction trade work is associated with longitudinal changes in estimated glomerular filtration rate (eGFR), a key indicator of kidney function.
Sammy Almashat, John M. Dement, Marianne Cloeren, Knut Ringen, Miles Fisher, Richard Rinehart   +5 more
wiley   +1 more source

Genetic and environmental factors associated with alteration of filtration slit proteins and their functions: a scoping review

Frontiers in Nephrology
BackgroundFiltration slit proteins are important for maintaining the integrity of the glomerular filtration barrier. Genetic mutations and environmental factors can disrupt their structure and functions, leading to proteinuria and kidney diseases.
Aolat Adepeju Adepoju, Mubarak Abubakar Muhammad, Mubashir Mayowa Adamson, Shakirudeen Abdulqodri Adewale, Adedeji Tayyib Adekunle, Lekan Sheriff Ojulari, Abdullateef Isiaka Alagbonsi, Abdullateef Isiaka Alagbonsi   +7 more
doaj   +1 more source