Results 1 to 10 of about 222,938 (359)
GLUCAGON ANTIBODIES AND AN IMMUNOASSAY FOR GLUCAGON* [PDF]
Journal of Clinical Investigation, 1961 Roger H. Unger +3 more
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Frontiers in Pharmacology, 2023 Olanzapine is a second-generation antipsychotic (SGA) used in the treatment of schizophrenia and several on- and off-label conditions. While effective in reducing psychoses, acute olanzapine treatment causes rapid hyperglycemia, insulin resistance, and ...
Kyle D. Medak +11 more
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Biology, 2022 Vasoactive Intestinal Peptide binds with high affinity to VPAC1R and VPAC2R, thus regulating key physiologic functions. Previously, we documented in VIP−/− mice a leaner body phenotype and altered metabolic hormones.
Daniel Sanford +7 more
doaj +1 more source
The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes
Endocrine Connections, 2021 Objective: Glucagon and amino acids may be regulated in a feedback loop called the liver-alpha-cell axis with alanine or glutamine as suggested signal molecules.
Julia Otten +7 more
doaj +1 more source
Postprandial dysfunction in fatty liver disease
Physiological Reports, 2023 Fatty liver disease has mainly been characterized under fasting conditions. However, as the liver is essential for postprandial homeostasis, identifying postprandial disturbances may be important.
Josephine Grandt +13 more
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Scientia Pharmaceutica, 2022 Glucagon is a polypeptide hormone that serves as an essential therapeutic agent in the emergency treatment of hypoglycemia. Recently, the first generic glucagon for injection was approved. However, unlike its brand name counterpart, which is produced via
Zhongli Bao +3 more
doaj +1 more source
Glucagon Receptor Signaling and Glucagon Resistance [PDF]
International Journal of Molecular Sciences, 2019 Hundred years after the discovery of glucagon, its biology remains enigmatic. Accurate measurement of glucagon has been essential for uncovering its pathological hypersecretion that underlies various metabolic diseases including not only diabetes and liver diseases but also cancers (glucagonomas).
Lina Janah +8 more
openaire +5 more sources
Frontiers in Endocrinology, 2020 IntroductionIn the UK, the fasting plasma concentrations of a panel of gut hormones (comprising vasoactive intestinal peptide (VIP), gastrin, pancreatic polypeptide (PP), glucagon, somatostatin and chromogranin A) are measured to evaluate patients who ...
Olivia L. Butler +6 more
doaj +1 more source
Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia
Endocrinology, Diabetes & Metabolism Case Reports, 2016 Introduction: In healthy carriers of the T allele of the transcription factor 7-like 2 (TCF7L2), fasting plasma glucagon concentrations are lower compared with those with the C allele.
Peter L Kristensen +9 more
doaj +1 more source
Fasting and Glucagon Stimulate Gene Expression of Pyruvate Dehydrogenase Kinase 4 in Chickens
The Journal of Poultry Science, 2017 The excessive accumulation of body fat has become a serious problem in the broiler industry. However, the molecular mechanisms underlying the regulation of lipid metabolism-related genes in broiler chickens are not fully understood.
Kazuhisa Honda +5 more
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