Glucagon-like peptide-1 and glucagon-like peptide-2 regulation during human liver regeneration [PDF]
Scientific Reports, 2023 Accumulating evidence suggests that metabolic demands of the regenerating liver are met via lipid metabolism and critical regulators of this process. As such, glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-2 (GLP-2) critically affect hepatic ...
Markus Ammann +9 more
doaj +4 more sources
Protective potential of glucagon like peptide 2 (GLP-2) against the neurodegeneration [PDF]
Neural Regeneration Research, 2019 Neurodegeneration consists in loss of neuron specific types, pattern and distribution, leading to progressive dysfunctions of the central nervous system.
Antonella Amato, Flavia Mulè
doaj +4 more sources
High fructose rewires gut glucose sensing via glucagon-like peptide 2 to impair metabolic regulation in mice [PDF]
Molecular MetabolismObjective: Increased fructose consumption contributes to type 2 diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD), but the mechanisms are ill-defined.
Eya Sellami +5 more
doaj +2 more sources
Glucagon-like peptide 2 (GLP-2) in bovine colostrum and transition milk [PDF]
Heliyon, 2021 Bovine colostrum contains growth factors, cytokines, hormones, and enzymes, which have important roles in stimulating gastrointestinal development of neonatal calves. In the present study, we measured the concentration of glucagon-like peptide 2 (GLP-2),
Yudai Inabu +8 more
doaj +2 more sources
Glucagon-like peptide-1 and glucagon-like peptide-1 receptor agonists in the treatment of type 2 diabetes [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2017 The prevalence of type 2 diabetes (T2D) is increasing worldwide. Patients with T2D suffer from various diabetes-related complications. Since there are many patients with T2D that cannot be controlled by previously developed drugs, it has been necessary ...
Seungah Lee, Dong Yun Lee
doaj +3 more sources
Evaluation of the relationship between plasma glucagon-like peptide-2 and gastrointestinal dysbiosis in canine chronic enteropathies. [PDF]
PLoS ONEChronic enteropathies are a common cause of morbidity in dogs and are associated with disruption of the normal gastrointestinal mucosal barrier. The objective of this prospective study was to determine the association between measures of gastrointestinal
Caylie D Voudren +3 more
doaj +2 more sources
An updated overview of glucagon-like peptide-2 analog trophic therapy for short bowel syndrome in adults [PDF]
Journal of International Medical Research, 2022 Short bowel syndrome (SBS) is a clinical condition characterized by a failure to achieve optimal intestinal adaptation, which is necessary to maintain oral/enteral autonomy.
Changzhen Zhu, Yuanxin Li
doaj +2 more sources
Glucagon-Like Peptide-2 Analogue ZP1849 Augments Colonic Anastomotic Wound Healing [PDF]
Gastroenterology Research and Practice, 2020 Background. The enteroendocrine hormone glucagon-like peptide- (GLP-) 2 is a potent trophic factor in the gastrointestinal tract. The GLP-2 receptor (GLP-2R) is expressed in the stroma of the large bowel wall, which is the major therapeutic target area ...
Marie Kjaer +10 more
doaj +2 more sources
Glucagon-Like Peptide-2: New Insights-New Questions [PDF]
Canadian Journal of Gastroenterology, 2001 Gordon R Greenberg
doaj +3 more sources
Frontiers in Endocrinology, 2021 ObjectiveNon-alcoholic fatty liver disease is highly prevalent in patients with type 2 diabetes mellitus. Studies on glucagon-like peptide-1 receptor agonists for the treatment of non-alcoholic fatty liver disease have reported promising results. Despite
Chloe Wong +12 more
doaj +1 more source