Results 91 to 100 of about 42,175 (206)

Distinct phosphorylation clusters determines the signalling outcome of the free fatty acid receptor FFA4/GPR120 [PDF]

, 2016
It is established that long-chain free fatty acids including ω-3 fatty acids mediate an array of biological responses through members of the free fatty acid receptor family, which includes FFA4.
Alvarez-Curto, Elisa, Butcher, Adrian J., Hudson, Brian D., Miller, Ashley M., Milligan, Graeme, Prihandoko, Rudi, Tobin, Andrew B., Ulven, Trond   +7 more
core   +2 more sources

The extrapancreatic effects of glucagon-like peptide-1 and related peptides [PDF]

, 2009
Context: Glucagon-like peptide-1 (GLP-1) 7-36 amide, an insulinotropic hormone released from the intestinal L cells in response to nutrient ingestion, has been extensively reviewed with respect to -cell function.
Abu Hamdah, Rania, Rabiee, Atoosa, Meneilly, Graydon S., Shannon, Richard P., Andersen, Dana K., Elahi, Dariush   +5 more
core   +1 more source

The Brain-Gut-Microbiome Axis. [PDF]

, 2018
Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir, Martin, Clair R, Mayer, Emeran A, Osadchiy, Vadim   +3 more
core   +2 more sources

Imeglimin enhances glucagon secretion through an indirect mechanism and improves fatty liver in high‐fat, high‐sucrose diet‐fed mice

Journal of Diabetes Investigation
Aims/Introduction Imeglimin is a recently approved oral antidiabetic agent that improves insulin resistance, and promotes insulin secretion from pancreatic β‐cells.
Osamu Kikuchi, Yuichi Ikeuchi, Masaki Kobayashi, Yoko Tabei, Hiromi Yokota‐Hashimoto, Tadahiro Kitamura   +5 more
doaj   +1 more source

Peptidylglycine monooxygenase activity of monomeric species of growth hormone

Heliyon, 2019
C-terminal α-amidation of peptides is an important event in the course of pro-hormone and neuropeptide processing; it is a modification that contributes to the biological activity and stability of about 25 peptides in neural and endocrine systems.
John Donlon, Patrick Ryan
doaj   +1 more source

Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling

Neural Plasticity, 2015
Hormones and peptides involved in glucose homeostasis are emerging as important modulators of neural plasticity. In this regard, increasing evidence shows that molecules such as insulin, insulin-like growth factor-I, glucagon-like peptide-1, and ghrelin ...
Marco Mainardi, Salvatore Fusco, Claudio Grassi   +2 more
doaj   +1 more source

Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats

, 2017
There is a well-documented association between cyclic changes to food intake and the changing ovarian hormone levels of the reproductive cycle in female mammals.
Johnson, Michelle L., Saffrey, M. Jill, Taylor, Victoria J.   +2 more
core   +1 more source

Protein folding, protein structure and the origin of life: Theoretical methods and solutions of dynamical problems [PDF]

Theoretical methods and solutions of the dynamics of protein folding, protein aggregation, protein structure, and the origin of life are discussed. The elements of a dynamic model representing the initial stages of protein folding are presented.
Weaver, D. L.
core   +1 more source

Frequently asked questions to the 2023 Obesity Medicine Association Position Statement on Compounded Peptides: A call for action

Obesity Pillars
Background: In 2023, the Obesity Medicine Association (OMA) published “Compounded peptides: An Obesity Medicine Association Position Statement.” Since this publication, the use of compounded peptides for the treatment of obesity has continued to evolve ...
Harold Edward Bays, Angela Fitch, Carolynn Francavilla Brown, Courtney Younglove, Sandra M. Christensen, Lydia C. Alexander   +5 more
doaj   +1 more source

Glucagon-like Peptides (GLP-1) Perspectives in Synucleinopathies Treatment. [PDF]

Mov Disord Clin Pract, 2018
Foltynie T, Athauda D.
europepmc   +1 more source