Results 131 to 140 of about 42,521 (302)

Bile Acids as Selective Gatekeepers of Dietary Lipid Absorption: Mechanistic Insights and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Their work provides evidence in murine models that the bile acid pool may function as a tunable filter whose selectivity for different fatty acids depends on bile acid concentration and composition. This framework suggests a selective decoupling of the absorption of excessive saturated fatty acids (SFAs) from that of beneficial polyunsaturated
Hao Wang, Yue Yang, Yulong Zhang, Yinling Li, Xuemei Ma, Haitao Wang   +5 more
wiley   +1 more source

Quality of life for pediatric patients with short bowel syndrome‐associated intestinal failure treated with teduglutide

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The complex care needs of pediatric patients with short bowel syndrome‐associated intestinal failure (SBS‐IF) can negatively impact the health‐related quality of life (HRQoL) of patients and their caregivers. We assessed the impact of teduglutide on HRQoL of pediatric patients with SBS‐IF.
Danielle Wendel, Paul W. Wales, Samuel Kocoshis, Robert Venick, Beth Carter, Valeria Cohran, Cheney Matthews, Bram P. Raphael, Ian Robinson, Susan Hill   +9 more
wiley   +1 more source

Retrospective chart review of immobilized lipase cartridge use in children with short bowel syndrome

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract This retrospective, single‐center chart review studied the use of an in‐line, immobilized lipase cartridge (ILC) in children with short bowel syndrome (SBS) at Children's Mercy Hospital. For parenteral nutrition (PN)‐dependent patients, the primary endpoint was enteral feeding progression, evaluated by comparing monthly change from baseline in
Elizaveta Khenner, Jennifer L. Morton, Laura Green, Ashlee Yoder, Kayla Paul, Ann E. Remmers, William O. San Pablo   +6 more
wiley   +1 more source

Outcomes and adverse effects of teduglutide treatment with periodic withdrawal in pediatric short bowel patients

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives We evaluated the efficacy and safety of teduglutide in a real‐world cohort in which national reimbursement policies required treatment interruptions. The primary outcomes were reduction in parenteral support (PS) and treatment‐related adverse effects, and the secondary outcome was the impact of the mandated withdrawal periods ...
Riikka Gunnar, Annika Mutanen, Mikko P. Pakarinen, Laura Merras‐Salmio   +3 more
wiley   +1 more source

Associations Between GLP‐1 Receptor Agonists and Alopecia: A Multi‐Centre Retrospective Analysis and Public Interest Trends

JEADV Clinical Practice, EarlyView.
ABSTRACT Background There is a growing body of literature suggesting that GLP‐1 receptor agonists (GLP‐1RAs) may be associated with hair loss; however, primary literature is sparse. Additionally, it is not well‐established which types of hair loss may be associated with GLP‐1RA use. Objectives This study aims to assess associations between GLP‐1RAs and
Lauren M. Ching, Christopher A. Guirguis, Joe K. Tung   +2 more
wiley   +1 more source

Frequently asked questions to the 2023 Obesity Medicine Association Position Statement on Compounded Peptides: A call for action

Obesity Pillars
Background: In 2023, the Obesity Medicine Association (OMA) published “Compounded peptides: An Obesity Medicine Association Position Statement.” Since this publication, the use of compounded peptides for the treatment of obesity has continued to evolve ...
Harold Edward Bays, Angela Fitch, Carolynn Francavilla Brown, Courtney Younglove, Sandra M. Christensen, Lydia C. Alexander   +5 more
doaj   +1 more source

Glucagon-like Peptides (GLP-1) Perspectives in Synucleinopathies Treatment. [PDF]

Mov Disord Clin Pract, 2018
Foltynie T, Athauda D.
europepmc   +1 more source

Protein folding, protein structure and the origin of life: Theoretical methods and solutions of dynamical problems [PDF]

Theoretical methods and solutions of the dynamics of protein folding, protein aggregation, protein structure, and the origin of life are discussed. The elements of a dynamic model representing the initial stages of protein folding are presented.
Weaver, D. L.
core   +1 more source

Dermatological Manifestations of Glucagon‐Like Peptide‐1 Receptor Agonists

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‑1 RAs) play a pivotal role in treating type 2 diabetes. Despite their widespread use, their dermatological manifestations remain under‐recognized, hence the interest of this systematic review. Objectives This systematic review aims to assess dermatological manifestations associated with
Nour Ghostine, Maya Halabi‐Tawil
wiley   +1 more source

Oral peptide therapeutics for diabetes treatment: State-of-the-art and future perspectives

Acta Pharmaceutica Sinica B
Diabetes, characterized by hyperglycemia, is a major cause of death and disability worldwide. Peptides, such as insulin and glucagon-like peptide-1 (GLP-1) analogs, have shown promise as treatments for diabetes due to their ability to mimic or enhance ...
Bingwen Ding, Zhu Zhu, Cong Guo, Jiaxin Li, Yong Gan, Miaorong Yu   +5 more
doaj   +1 more source