Results 201 to 210 of about 42,521 (302)

Genomic Investigations Unveil the Genetic Underpinnings of Environmental Adaptation in African Goat Populations

Integrative Zoology, EarlyView.
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng, Yihua Wang, Yiyuan Zhang, Lei Gao, Lili Wu, Shuping Wang, Yiyang Gao, Wanlu Shi, Kaixin Lu, Rong Deng, Junting Li, Jing Han, Xiaohui Lu, Yujie Liu, Xiaojiao Tang, Yunxia Zhang, Guoyin Li, Li Huang, Mingsheng Yang, Xiaoyan Li   +19 more
wiley   +1 more source

SEL1L-HRD1 ER-associated degradation facilitates prohormone convertase 2 maturation and glucagon production in islet α cells. [PDF]

Nat Commun
Zhu W, Pan L, Cui X, Russo AC, Ray R, Pederson B, Wei X, Lin LL, Torres M, Hafner H, Gregg B, Shrestha N, Liu C, Naji A, Arvan P, Sandoval DA, Lindberg I, Qi L, Reinert RB.   +18 more
europepmc   +1 more source

Effectiveness of a Psychiatrist‐Led Clinic for Metabolic Health in Severe Mental Illness: A Retrospective Chart Review Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Psychotropic medications are associated with serious metabolic adverse effects, which contribute to an increased risk of cardiometabolic comorbidities in patients with severe mental illness (SMI). Several intervention strategies are available to mitigate these metabolic adverse effects; however, data on their utility in real‐world ...
Nicolette Stogios, Femin Prasad, Riddhita De, Kateryna Maksyutynska, Akash PrasannaKumar, Vittal Korann, Tariq Ahmed, Marcos Sanches, Leah Burton, Mohammed A. Alarabi, Tanner Isinger, Michelle Desanti, Rebecca Oliveira, Daphne J. Korczak, Ariel Graff‐Guerrero, Gary Remington, Margaret K. Hahn, Sri Mahavir Agarwal   +17 more
wiley   +1 more source

Glucagon-like peptide-1 receptor agonists for obesity: Growing popularity met with growing questions over safety. [PDF]

PLoS Med
Chao AM, Gilden A, Wadden TA.
europepmc   +1 more source

A genetically informed cross‐lagged twin study of the longitudinal association between addiction‐related behaviors and obesity

Addiction, EarlyView.
Abstract Background and aims Addiction‐related behaviors, such as loss of control eating (LOC), cigarette smoking and alcohol consumption, have been associated with high body mass index (BMI). This study aimed to assess genetic and environmental contributions to these associations over time.
Baiyu Qi, Heather M. Highland, Mariaelisa Graff, Cynthia M. Bulik, Soo Hyun Rhee, Michael C. Stallings, John K. Hewitt, Daniel E. Gustavson, Chandra A. Reynolds, Kari E. North, Melissa A. Munn‐Chernoff   +10 more
wiley   +1 more source

Xenin-Derived Peptides: Multifaceted Regulators and Therapeutic Innovations in Metabolic Diseases. [PDF]

Drug Des Devel Ther
Gong B, Liu X, Hu G, Li T, Chen F, Sun X, Sun L, Xu Y.   +7 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

The expanding landscape of the glucagon signaling network: mechanisms and outcomes.

Endocrinology
Foollee A, Wu Y, Rusu PM, Rose AJ.
europepmc   +1 more source

Trends in 1-year persistence and adherence among initiators of high-potency, weight loss-indicated glucagon-like peptide 1 receptor agonists. [PDF]

J Manag Care Spec Pharm
Marshall LZ, Gleason PP, Friedlander N, Farley J, Urick BY.   +4 more
europepmc   +1 more source

Peri‐operative fasting in adults: an international, multidisciplinary consensus statement

Anaesthesia, EarlyView.
Summary Introduction Evidence suggests that existing pre‐operative fasting guidelines are associated with prolonged fasting times. Prolonged fasting, particularly from clear liquids, has the potential to harm patients through reduced peri‐operative wellbeing; impaired glucose metabolism and peri‐operative inflammatory response; delayed return of bowel ...
Anne Rüggeberg, Kariem El‐Boghdadly, Federico Bilotta, Marta Dias Vaz, Anne Marie Camilleri Podesta, Ib Jammer, Ehrenfried Schindler, Jamie Elmawieh, Alexander Nagrebetsky, Stakeholders, Christiane Beck, Maximilian Heinz Beck, David Borshoff, Lionel Bouvet, Madjid Boukantar, David Bunting, Sharon Carey, Mirka Cikkelova, Matthew Checketts, Michael Clarius, Aaron Conway, Marc Coppens, Rafaela Coutinho, Arianna Dal Buono, Pradeep A Dongare, Richard Dutton, Dilay Erbaş, David Ferreira, Adriano Friganovic, Peter Frykholm, Adrian W Gelb, Andrew M Goldsweig, Steven Green, Steven Greenberg, Jana G Hashash, Helen Haskell, Arvid Steinar Haugen, Dorthe Hjort Jakobson, Erin Hommel, Ryan Howle, Jaime Hyman, Mohua Jain, Girish P Joshi, Noelleen Kiprillis, Inci Kirtil, Shanu Kothari, Peter Kranke, Dileep N Lobo, Benjamin Loveday, Michael Margarson, Phuong Markman, Marije Marsman, Carmen Mazilu, Viorica Nedelcu, Anahi Perlas, Susanna Price, Finn Radtke, Kate Rivett, Michael Sander, Faiz Shariff, Aistė Štaraitė, Pietro Paolo Tamborrino, Panagiota Tsikala, Arnaldo Valedon, Harm HJ Van Noort, Matthew Wiles, Meryem Yilmaz, Marko Zdravkovic   +67 more
wiley   +1 more source