Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches
PROTEOMICS, EarlyView.
Paul Perco+7 more
wiley +1 more source
Detection of Insulin in Insulin-Deficient Islets of Patients with Type 1 Diabetes. [PDF]
Krivova Y+4 more
europepmc +1 more source
Studies on the Insulin-like Activity and Glucagon-like Activity of Blood in Diabetic Subjects
Akira Matsuoka+3 more
openalex +2 more sources
Phosphorylation of an RNA‐Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging
Evolutionary conserved Hippo/Mst1 signaling non‐canonically regulates the stability of mRNAs through directly phosphorylating a subset of RNA binding proteins to stabilize lipolytic mRNAs. Hpo pathway contributes to the regulation of Drosophila lifespan by modulating the expression and activity of Me31b/RCK, which subsequently affects mRNA levels of ...
Eunbyul Yeom+26 more
wiley +1 more source
Female glucagon receptor knockout mice are prone to steatosis but resistant to weight gain when fed a MASH-promoting GAN diet and a high-fat diet. [PDF]
Galsgaard KD+9 more
europepmc +1 more source
Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) are effective for treating obesity (BMI ≥30) and are being investigated as a novel treatment for alcohol use disorder (AUD). This secondary analysis of a randomized clinical trial evaluated the effect of exenatide versus placebo on alcohol consumption using phosphatidylethanol (PEth) in 30 AUD ...
Mathias E. Jensen+6 more
wiley +1 more source
Preoperative liraglutide modulates control of fat and glucose metabolism during cardiopulmonary bypass surgery. [PDF]
van Wilpe R+5 more
europepmc +1 more source
ABSTRACT Background Metformin shows potential in combating clozapine‐induced weight gain (CIWG). However, current evidence for its use remains limited. Through an audit we determined the prevalence of metformin use among clozapine‐treated patients and its impact on weight and waist circumference (WC).
Bee Leng Per+5 more
wiley +1 more source
Effects of different grain types on nutrient apparent digestibility, glycemic responses, and fecal VFA content in weaned foals. [PDF]
Huang X+8 more
europepmc +1 more source
Effects of glucagon and insulin on cytoplasmic protein phosphorylation in hepatocytes
Joseph Avruch+3 more
openalex +1 more source