Results 211 to 220 of about 214,982 (356)

Light‐Mediated Insulin and Amylin Secretion: Influence of Irradiation Parameters in Optogenetically Modified Mouse‐Pancreatic β Cells

open access: yesJournal of Biophotonics, EarlyView.
This study demonstrates variation in photo‐induced secretion of insulin and amylin from Channelrhodopsin‐2 expressing MIN6 cells under different irradiation conditions. For the first time, an alteration in the relative ratio of amylin: insulin is observed with varying irradiation conditions.
Nidhi Maharwal   +3 more
wiley   +1 more source

Intranasal Naloxone During Recurrent Exercise in Individuals with Type‐1 Diabetes Mellitus: Evaluation of the Clinical Predictors of Pharmacokinetics and Exposure–Response

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Impaired awareness of hypoglycemia (IAH) impacts 25%–30% of individuals with type 1 diabetes mellitus (T1D), potentially leading to severe outcomes due to reduced symptom perception. Naloxone, a mu‐opioid receptor antagonist, shows promise as a preventive measure against IAH.
Omar N. Al Yacoub   +9 more
wiley   +1 more source

GLP-1 and GIP may play a role in long-term weight trajectories after gastric bypass. [PDF]

open access: yesFront Endocrinol (Lausanne)
Andrade S   +9 more
europepmc   +1 more source

Glucose-Insulin-Potassium Therapy Guided by a Glucose-Controlled Insulin Infusion System in Acute Myocardinal Infarction [PDF]

open access: yes, 1985
Ball, P.   +10 more
core   +1 more source

Glucagon‐releasing activity of guanidine compounds in mouse pancreatic islets [PDF]

open access: bronze, 1976
José Marco   +3 more
openalex   +1 more source

Utilization of Proteomic Measures for Early Detection of Drug Benefits and Adverse Effects

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Recognition of benefits and adverse effects of therapies in earlier clinical trial phases could improve the safety, efficiency, and cost of clinical trials. Using four clinical trials representing a diverse set of diseases and drug classes (EXSCEL: exenatide/GLP‐1 RA, SUGAR‐DM‐HF: empagliflozin/SGLT2i, PRADA: epirubicin/anthracycline, and ...
Jessica Chadwick   +17 more
wiley   +1 more source

Synthesis and isolation of a glucagon antagonist [PDF]

open access: bronze, 1979
Marvin D. Bregman, Victor J. Hruby
openalex   +1 more source

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