Results 211 to 220 of about 114,692 (269)

Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches

open access: yes
PROTEOMICS, EarlyView.
Paul Perco   +7 more
wiley   +1 more source

Detection of Insulin in Insulin-Deficient Islets of Patients with Type 1 Diabetes. [PDF]

open access: yesLife (Basel)
Krivova Y   +4 more
europepmc   +1 more source

Phosphorylation of an RNA‐Binding Protein Rck/Me31b by Hippo Is Essential for Adipose Tissue Aging

open access: yesAging Cell, EarlyView.
Evolutionary conserved Hippo/Mst1 signaling non‐canonically regulates the stability of mRNAs through directly phosphorylating a subset of RNA binding proteins to stabilize lipolytic mRNAs. Hpo pathway contributes to the regulation of Drosophila lifespan by modulating the expression and activity of Me31b/RCK, which subsequently affects mRNA levels of ...
Eunbyul Yeom   +26 more
wiley   +1 more source

Female glucagon receptor knockout mice are prone to steatosis but resistant to weight gain when fed a MASH-promoting GAN diet and a high-fat diet. [PDF]

open access: yesPhysiol Rep
Galsgaard KD   +9 more
europepmc   +1 more source

Blood phosphatidylethanol measurements indicate GLP‐1 receptor stimulation causes delayed decreases in alcohol consumption

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) are effective for treating obesity (BMI ≥30) and are being investigated as a novel treatment for alcohol use disorder (AUD). This secondary analysis of a randomized clinical trial evaluated the effect of exenatide versus placebo on alcohol consumption using phosphatidylethanol (PEth) in 30 AUD ...
Mathias E. Jensen   +6 more
wiley   +1 more source

The Impact of Metformin on Weight and Waist Circumference in Patients Treated With Clozapine: A One‐Year Retrospective Cohort Study

open access: yesActa Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Metformin shows potential in combating clozapine‐induced weight gain (CIWG). However, current evidence for its use remains limited. Through an audit we determined the prevalence of metformin use among clozapine‐treated patients and its impact on weight and waist circumference (WC).
Bee Leng Per   +5 more
wiley   +1 more source

Effects of glucagon and insulin on cytoplasmic protein phosphorylation in hepatocytes

open access: hybrid, 1978
Joseph Avruch   +3 more
openalex   +1 more source

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