Results 231 to 240 of about 140,006 (312)

GLP-1, GIP, and Glucagon Excursions During a Mixed Meal Tolerance Test in Young and Lean South Asians Versus Europids. [PDF]

Diabetes Obes Metab
Hoekx CA, Brinkman LBD, van Eenige R, Kooijman S, Muskiet MHA, Jazet IM, Martinez-Tellez B, Rensen PCN, Boon MR.   +8 more
europepmc   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

eNAMPT induces alpha-cell mass expansion but impaired glucagon counter regulatory response.

Endocrinology
Sayers SR, Gesheva VS, Varghese JJ, Beavil R, Zhao M, Cheah Y, Hopkins D, Fine NHF, Hasib A, Hodson DJ, Caton PW.   +10 more
europepmc   +1 more source

Genomic Investigations Unveil the Genetic Underpinnings of Environmental Adaptation in African Goat Populations

Integrative Zoology, EarlyView.
This study integrates genomics and landscape genetics to analyze African goat environmental adaptation. Analyzing 1591 samples, it finds population structure differentiates geographically into four groups, with gene flow between wild Yura goats and North Africans.
Weifeng Peng, Yihua Wang, Yiyuan Zhang, Lei Gao, Lili Wu, Shuping Wang, Yiyang Gao, Wanlu Shi, Kaixin Lu, Rong Deng, Junting Li, Jing Han, Xiaohui Lu, Yujie Liu, Xiaojiao Tang, Yunxia Zhang, Guoyin Li, Li Huang, Mingsheng Yang, Xiaoyan Li   +19 more
wiley   +1 more source

Hypothalamus-liver talks: whispers in the language of metabolism. [PDF]

Rev Endocr Metab Disord
Ferreira V, Fernández-González I, Vattathara JJ, Rodríguez-Díaz A, Fernández-Sanmartín P, Diéguez C.   +5 more
europepmc   +1 more source

Use of Glucagon‐Like Peptide 1 Receptor Agonists and the Associated Risk of Hospitalisation in Bipolar Disorder, From a Nationwide Cohort, 2009–2024

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Diabetes, obesity and bipolar disorder often co‐occur and may have shared pathophysiology. Glucagon‐like peptide 1 receptor agonists (GLP‐1RA) treat diabetes and obesity but their impact on bipolar disorder is unknown. In this era of stagnated pharmacotherapy, we examined psychiatric hospitalisation and absence from work due to ...
Heidi Taipale, Mark Taylor, Markku Lähteenvuo, Ellenor Mittendorfer‐Rutz, Antti Tanskanen, Jari Tiihonen   +5 more
wiley   +1 more source

Changes in incretin hormone concentrations after pancreaticoduodenectomy: a systematic review and exploratory meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Grząsiak-Kraj O, Kraj T, Poznański K, Szmiel A, Strzelczyk J.   +4 more
europepmc   +1 more source

A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies

Addiction, EarlyView.
Abstract Background and aims Evidence on the causal impact and corresponding risk relationships between dimensions of alcohol consumption and health outcomes continues to evolve, with some contradictory findings across study designs. This review aimed to update current knowledge on causality and risk relationships to inform global and national ...
Sinclair Carr, Ana Lucia Espinosa Dice, Gerhard E. Gmel Sr., Ahmed S. Hassan, Kevin D. Shield, Jürgen Rehm   +5 more
wiley   +1 more source

Recent advances in incretin biology and therapeutics: From glucose-dependent insulinotropic polypeptide reappraisal to next-generation agonists. [PDF]

J Diabetes Investig
Kubota S, Seino Y, Yabe D.
europepmc   +1 more source

Impact of bariatric surgery on alcohol‐use disorder and alcohol‐related liver disease: A retrospective study

Addiction, EarlyView.
Abstract Background and aims Increased risk of alcohol dependence is recognised following bariatric surgery. Modified gastrointestinal anatomy and neurohormonal profiles lead to altered alcohol metabolism, peak blood alcohol concentrations and enhanced reward circuits and cravings.
Thomas J. Williams, Andrew J. Palmer, Jason P. Connor, Gerald Holtmann, Paul J. Clark   +4 more
wiley   +1 more source