A new paradigm of islet adaptations in human pregnancy: insights from immunohistochemistry and proteomics. [PDF]
Seedat F+9 more
europepmc +1 more source
Erythematous Papules and Plaques in an Infant Receiving Glucagon Therapy
JEADV Clinical Practice, EarlyView.
Sara Al Janahi+4 more
wiley +1 more source
A geriatrician's approach to managing the complex older adult with obesity
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley +1 more source
GLP‐1 Receptor Agonists for Obstructive Sleep Apnea: An Otolaryngologist's Prescription?
The Laryngoscope, EarlyView.
Alina Zgardau+3 more
wiley +1 more source
Evolution of multidisciplinary obesity treatments: past, present, and future role of nutrition
Abstract Obesity is a complex chronic disease requiring lifelong comprehensive treatment. In addition to lifestyle counseling that improves nutrition and physical activity, a promising new generation of obesity medications has been added to bariatric procedures as therapeutic options to achieve weight reduction and improve health outcomes.
Steven B. Heymsfield+6 more
wiley +1 more source
The 'Designer' Artificial Pancreas: How Does Current Technology Mimic Pancreatic Physiology? [PDF]
Ayliffe Daly L.
europepmc +1 more source
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu+13 more
wiley +1 more source
Proinflammatory cytokine-induced alpha cell impairment in human islet microtissues is partially restored by dual incretin receptor agonism. [PDF]
Henriksen K+8 more
europepmc +1 more source
ABSTRACT Objective This study aimed to evaluate the added effect of acarbose to orlistat on relative weight loss in the novel antiobesity medication EMP16. Methods In this 6‐month double‐blind trial, 240 individuals with obesity or overweight and comorbidities were randomized equally into three groups: (1) EMP16 (120 mg modified release orlistat/40 mg ...
Ulf Holmbäck+7 more
wiley +1 more source
Allosteric communication mechanism in the glucagon receptor. [PDF]
van der Velden WJC+2 more
europepmc +1 more source