Results 41 to 50 of about 214,982 (356)

Hypothalamically-Induced Insulin Release and its Potentiation During Oral and Intravenous Glucose Loads [PDF]

, 1984
Male Wistar rats were provided with bilateral cannulas in the lateral hypothalamic area (LHA) and cannulas in the left and right jugular vein. Freely moving rats provided in this way with cannulas were infused with transmitters in the LHA and with ...
A.B. Steffens, Bernstein, Berthoud, Berthoud, Bloom, Bloom, Daniel, De Groot, De Jong, E.C. Lotter, F. Kuipers, Frohman, Frohman, G. Flik, Henquin, Inoue, Iversen, Iversen, Kaneto, Kaneto, Kaneto, Kaneto, Karam, Matsushita, McCaleb, Moltz, P.G.M. Luiten, Robertson, Shimazu, Shimazu, Shimazu, Steffens, Steffens, Strubbe, Strubbe, Strubbe   +35 more
core   +4 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis burden, 1990–2021

Arthritis Care &Research, Accepted Article.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen, Lei Si, David J Hunter, Lei Zhang, Zhe‐Sheng Chen, Xiaomeng Wang, Vicky Duong, Zhounan Zhou, Peihua Cao, Han Cen, Su'an Tang, Tianyu Chen, Houjun Xue, Zhaohua Zhu, Changhai Ding   +14 more
wiley   +1 more source

Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

eLife, 2021
Insulin-induced hypoglycemia is a major treatment barrier in type-1 diabetes (T1D). Accordingly, it is important that we understand the mechanisms regulating the circulating levels of glucagon.
Angela Kim, Jakob G Knudsen, Joseph C Madara, Anna Benrick, Thomas G Hill, Lina Abdul Kadir, Joely A Kellard, Lisa Mellander, Caroline Miranda, Haopeng Lin, Timothy James, Kinga Suba, Aliya F Spigelman, Yanling Wu, Patrick E MacDonald, Ingrid Wernstedt Asterholm, Tore Magnussen, Mikkel Christensen, Tina Vilsbøll, Victoria Salem, Filip K Knop, Patrik Rorsman, Bradford B Lowell, Linford JB Briant   +23 more
doaj   +1 more source

Splanchnic metabolism of nutrients and hormones in steers fed alfalfa under conditions of increased absorption of ammonia and L-arginine supply across the portal-drained viscera [PDF]

, 2005
Effects of increased ammonia and/or arginine absorption on net splanchnic (portal-drained viscera [PDV] plus liver) metabolism of nonnitrogenous nutrients and hormones in cattle were examined.
Assan, Bergman, Bruggemann, C. K. Reynolds, Chalupa, D. E. Beever, Davenport, Davenport, Demigne, Elsasser, Fernandez, Gow, Hammerman, Huntington, Krebs, Kuhara, Lobley, Lobley, M. A. Lomax, Maltby, Meijer, Milano, Morgan, Newsholme, Prior, Prior, Reynolds, Reynolds, Reynolds, Reynolds, Reynolds, Reynolds, Reynolds, Reynolds, S. A. Maltby, Seal, Spires, Taniguchi, Titheradge, Tyrrell, Vicini, Visek, Waterlow   +42 more
core   +1 more source

Microscopically Adaptable Bioink Guide Cell Compartmentalization toward Morphogenesis of a Functional Vasculature‐Like System

Advanced Healthcare Materials, EarlyView.
Contractile vasculatures are fabricated through a one‐step bioprinting strategy. The adaptable microenvironment provided by ECM‐mimicking bioink triggers cell sorting and compartmentalization of endothelial cells and vascular smooth muscle cells toward a histological configuration by focal adhesion kinase‐mediated upregulation of cell adhesion and ...
Jun Chen, Yuqiong Wu, Jiarong Huang, Junjin Jie, Chan Huang, Di Zhang, Yuxin Huang, Rui Mao, Ming Zhao, Lin‐Ping Wu   +9 more
wiley   +1 more source

Er-Miao-Fang Extracts Inhibits Adipose Lipolysis and Reduces Hepatic Gluconeogenesis via Suppression of Inflammation

Frontiers in Physiology, 2018
High-fat-diet (HFD) feeding induces adipose dysfunction. This study aims to explore whether the Traditional Chinese Medical prescription Er-Miao-Fang could ameliorate adipose dysfunction and prevent hepatic glucose output.
Wenjun Zhao, Wenjun Zhao, Xin Feng, Baolin Liu, Jiechen Xian, Ning Zhang   +5 more
doaj   +1 more source

Low Fasting Concentrations of Glucagon in Patients with Very Long-Chain Acyl-CoA Dehydrogenase Deficiency

Metabolites, 2023
(1) Background: Deficiencies of mitochondrial fatty acid oxidation (FAO) define a subgroup of inborn errors of metabolism, with medium-chain acyl-CoA dehydrogenase deficiency (MCAD) and very long-chain acyl-CoA dehydrogenase deficiency (VLCAD) being two ...
Rasmus Stenlid, Hannes Manell, Rikard Seth, Sara Y. Cerenius, Azazul Chowdhury, Camilla Roa Cortés, Isabelle Nyqvist, Thomas Lundqvist, Maria Halldin, Peter Bergsten   +9 more
doaj   +1 more source

Small‐for‐size liver transplanted into larger recipient: A model of hepatic regeneration [PDF]

, 1994
Orthotopic liver transplantation was performed in 60 recipient rats weighing 200 to 250 gm. Sixty rats of the same strain were used as liver donors, 30 weighing 100 to 140 gm (small for size) and the other 30 weighing 200 to 250 gm (same size).
Carr, BI, Francavilla, A, Polimeno, L, Porter, KA, Starzl, TE, Sun, D, van Thiel, DH, Zeng, Q   +7 more
core   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

Advanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi, Junho Byun, Dongyoon Kim, Qiaoyun Li, Dongun Jin, Yeong‐jin Choi, Ho Sang Jung, Jaiwoo Lee, Yu‐Kyoung Oh   +8 more
wiley   +1 more source