Results 131 to 140 of about 721 (165)

CMS to compensate hospitals for inpatient use of fidaxomicin, glucarpidase

American Journal of Health-System Pharmacy, 2012
The government will pay acute care hospitals up to half the average cost of fidaxomicin or glucarpidase when given to Medicare-covered in-patients, the Centers for Medicare and Medicaid Services has decided for fiscal year 2013. This decision, affecting discharges occurring on or after October 1,
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Delayed Methotrexate Clearance Despite Carboxypeptidase-G2 (Glucarpidase) Administration in 2 Patients With Toxic Methotrexate Levels

Journal of Pediatric Hematology/Oncology, 2018
High-dose methotrexate has been a treatment for osteosarcoma; however, its nephrotoxic effects are considerable. Carboxypeptidase-G2 (glucarpidase) was approved by the US Food and Drug Administration in 2012 for treatment of toxic methotrexate levels.
Wyatt, Kirk, Cooper, Jeffrey, Scott, Katherine, Broomall, Eileen, Altaf, Sadaf, Hogan, Marie C., Rodriguez, Vilmarie, Khan, Shakila   +7 more
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Screening for and Identification of Novel Glucarpidase Producing Bacteria

The FASEB Journal, 2014
Antibody Directed Enzyme Prodrug Therapy (ADEPT) is a novel therapy which has already been implemented in cancer therapy to solve the problem of drug resistance and lack of tumor selectivity. Repeated cycles of (ADEPT) and the use of glucarpidase in detoxification of cytotoxic methotrexate (MTX) are desirable but are hindered by the induced human ...
Alqahtani, Alanood, Alyafei, Afrah, Abdallah, Fatma, Latiff, Aishah, Groves, Matthew, Dömling, Alex, Goda, Sayed   +6 more
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High-Dose Methotrexate (HDMTX) Induced Nephrotoxicity: Glucarpidase or Dialysis?

Journal of the American Society of Nephrology, 2022
Abhinaya Sridhar, Uzma Malik, Aromma Kapoor   +2 more
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Rechallenge With High-Dose Methotrexate After Treatment With Glucarpidase in Adult Patients With Lymphoma

JCO Oncology Practice
PURPOSE Limited evidence exists regarding methotrexate (MTX) resumption after patients with lymphoma receive glucarpidase for toxic MTX levels and acute kidney injury (AKI). METHODS This retrospective review included adults with lymphoma treated with glucarpidase after MTX at Mayo Clinic between January 31, 2020, and October 10, 2022.
Huong L. Truong, Jason N. Barreto, Kristin C. Mara, Paul J. Hampel, Ivana N. Micallef, Grzegorz S. Nowakowski, Gita Thanarajasingam, Carrie A. Thompson, Yucai Wang, Thomas E. Witzig, Sandra M. Herrmann, Nelson Leung   +11 more
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Glucarpidase/methotrexate

Reactions Weekly, 2022
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Glucarpidase treatment for methotrexate intoxication: a case report and review of the literature.

The Netherlands journal of medicine, 2018
High-dose methotrexate (MTX) induced acute kidney injury can lead to sustained high systemic MTX levels and severe toxicity. A 39-year-old man with lymphoblastic T-cell lymphoma was admitted to our intensive care unit with elevated serum creatinine and prolonged high serum MTX levels.
Boelens, A. D., Mathôt, R. A. A., Vlaar, A. P. J., Bouman, C. S. C.   +3 more
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Glucarpidase/methotrexate

Reactions Weekly, 2020
openaire   +1 more source

A second administration of glucarpidase in a different cycle of high-dose methotrexate: Is it safe and effective in adults?

Journal of Oncology Pharmacy Practice, 2021
Amalia Domingo-González, Santiago Osorio   +1 more
exaly  

The use of glucarpidase as a rescue therapy for high dose methotrexate toxicity – a review of pharmacological and clinical data

Expert Opinion on Drug Metabolism and Toxicology, 2023
Jakub Rosik, Łukasz Ustianowski, Bartosz Szostak   +2 more
exaly