Results 181 to 190 of about 460,157 (392)

Early Effects of Glucocorticoids on Nucleic Acid Metabolism of Rat Liver. [PDF]

, 1963
Kristian F. Jervell, Shona Pedersen, Lars Gunnar Sillén, Poul Nielsen, Jon Munch‐Petersen   +4 more
openalex   +1 more source

Incidence of Major Adverse Cardiovascular Events in Patients With Rheumatoid Arthritis Treated With JAK Inhibitors Compared With Biologic Disease‐Modifying Antirheumatic Drugs: Data From an International Collaboration of Registries

Arthritis &Rheumatology, EarlyView.
Objective Our objective was to assess the incidence of major adverse cardiovascular events (MACEs) in patients with rheumatoid arthritis (RA) treated with JAK inhibitors (JAKi), tumor necrosis factor inhibitors (TNFi), or biologic disease‐modifying antirheumatic drugs with other modes of action (bDMARD‐OMA) in a multicountry, real‐world population ...
Romain Aymon, Denis Mongin, Romain Guemara, Zubeyir Salis, Johan Askling, Denis Choquette, Catalin Codreanu, Daniela Di Giuseppe, Irini Flouri, Doreen Huschek, Kimme L. Hyrich, Florenzo Iannone, Tore K. Kvien, Burkhard F. Leeb, Dan Nordström, Lucia Otero‐Varela, Karel Pavelka, Manuel Pombo‐Suarez, Ana Rodrigues, Ziga Rotar, Prodromos Sidiropoulos, Sella A. Provan, Anja Strangfeld, Trokovic Nina, Jakub Zavada, Lianne Kearsley‐Fleet, Delphine S. Courvoisier, Axel Finckh, Kim Lauper   +28 more
wiley   +1 more source

ON THE MECHANISM OF PROTECTION OF ENDOTOXIN SHOCK BY GLUCOCORTICOIDS

, 1964
Tokuro FUKUDA, Mitsuo Okada, Takashi Kobayashi   +2 more
openalex   +2 more sources

EPINEPHRINE SHOCK, ITS RELATION TO PLASMA EPINEPHRINE LEVEL AND THE MECHANISM OF ITS PROTECTION BY GLUCOCORTICOID

, 1967
Tokuro FUKUDA, Hiroyuki Okuma, Namiyo HATA   +2 more
openalex   +2 more sources

Oral Glucocorticoid–Sparing Effect of Benralizumab in Severe Asthma

New England Journal of Medicine, 2017
Parameswaran Nair, S. Wenzel, K. Rabe, A. Bourdin, N. Lugogo, P. Kuna, P. Barker, Stephanie Sproule, S. Ponnarambil, M. Goldman   +9 more
semanticscholar   +1 more source

Aberrant Glycosylation of IgG in Children With Active Lupus Nephritis Alters Podocyte Metabolism and Causes Podocyte Injury

Arthritis &Rheumatology, EarlyView.
Objective Podocytes are integral to the maintenance of the glomerular filtration barrier. Their injury results in proteinuria and disease progression in lupus nephritis (LN). Aberrant IgG glycosylation drives podocyte injury in LN and leads to cytoskeletal rearrangement, motility changes, and decreased nephrin production.
Rhea Bhargava, Rohit Upadhyay, Cong Zhao, Prasad Katakam, Scott Wenderfer, Jing Chen, Hua He, Richard Cummings, Maria G. Tsokos, George C. Tsokos   +9 more
wiley   +1 more source

Inhibition of the Activities of Glutamic, Malic and Lactic Dehydrogenases by Glucocorticoids in Normal and Psoriatic Epidermis

, 1964
Ken Hashimoto, Mauray J. Tye, Walter F. Lever   +2 more
openalex   +1 more source

Adjunctive Glucocorticoid Therapy in Patients with Septic Shock

New England Journal of Medicine, 2018
B. Venkatesh, S. Finfer, Jeremy Cohen, D. Rajbhandari, Y. Arabi, R. Bellomo, L. Billot, Maryam Correa, P. Glass, M. Harward, C. Joyce, Qiang Li, C. McArthur, A. Perner, A. Rhodes, Kelly J Thompson, S. Webb, J. Myburgh   +17 more
semanticscholar   +1 more source

Effect of long‐term voclosporin treatment on renal histology in patients with active lupus nephritis with repeat renal biopsies

Arthritis &Rheumatology, Accepted Article.
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to three years; all patients received mycophenolate mofetil and low‐dose ...
Brad H. Rovin, Clarissa Cassol, Samir V. Parikh, Amit Saxena, Neil Solomons, Vanessa Birardi, Ernie Yap, Clint W. Abner, David R.W. Jayne, Robert B. Huizinga   +9 more
wiley   +1 more source

Gout and NLRP3 Inflammasome Biology

Arthritis &Rheumatology, EarlyView.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source