Results 181 to 190 of about 414,407 (362)
Biphasic Glucocorticoid Rhythm in One-Month-Old Infants: Reflection of a Developing HPA-Axis? [PDF]
Jonneke J. Hollanders +9 more
openalex +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong +14 more
wiley +1 more source
Unmasking Isolated Glucocorticoid Deficiency: Clinical Insights From 2 Cases. [PDF]
Singhal A +5 more
europepmc +1 more source
PF451 GLUCOCORTICOID INDUCED LEUCINE ZIPPER (GILZ) IS REQUIRED FOR HEMATOPOIETIC STEM CELL FUNCTION
Oxana Bereshchenko +6 more
openalex +1 more source
Identification of Compound Heterozygous CYP11A1 Variants via Reanalysis of Clinical Sequencing Data
ABSTRACT A molecular diagnosis is currently achievable in approximately 50% of patients assessed by clinical geneticists at tertiary care centres. Next‐Generation Sequencing Panels contain a defined group of genes associated with a clinically defined set of phenotypes.
Ana Acosta Bedón +10 more
wiley +1 more source
Platelet-to-neutrophil ratio and in-hospital mortality in pneumonia patients receiving glucocorticoid therapy: a multicenter retrospective cohort study. [PDF]
Lin J, Chen R, Xu S, Lin W.
europepmc +1 more source
ABSTRACT Biallelic pathogenic variants in AKR1D1 cause Δ4‐3‐oxosteroid 5β‐reductase deficiency, disrupt bile acid synthesis, and result in Congenital Bile Acid Synthesis defect type 2 (CBAS2). CBAS2 presents in infancy with cholestasis, coagulopathy, and failure to thrive.
Jade Hudson +3 more
wiley +1 more source

