Results 221 to 230 of about 254,141 (317)

The Effect of Benralizumab and Mepolizumab on Use of Oral Glucocorticoids in Patients With Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Objective The phase 3 MANDARA study demonstrated noninferiority of benralizumab versus mepolizumab for remission in patients with eosinophilic granulomatosis with polyangiitis (EGPA). More benralizumab‐treated patients achieved complete withdrawal of oral glucocorticoids (OGCs).
Parameswaran K. Nair, Bernhard Hellmich, Arnaud Bourdin, David R. W. Jayne, Florence Roufosse, Nader Khalidi, Lena Börjesson Sjö, Ying Fan, Christopher McCrae, Sofia Necander, Eva Rodríguez‐Suárez, Anat Shavit, Claire Walton, Peter A. Merkel, Michael E. Wechsler   +14 more
wiley   +1 more source

Examining Self-Reported Executive Function and Its Relationship to Patient-Reported Outcomes and Disease-Related Factors in Youth With Childhood-Onset Lupus: A Cross-Sectional Study. [PDF]

ACR Open Rheumatol
El Tal T, Jaffan J, Ledochowski J, Mossad SI, Ng L, Jeyanathan A, Davis AL, Hiraki L, Levy DM, Touma Z, Cunningham NR, Danguecan A, Knight A.   +12 more
europepmc   +1 more source

The role of sulfhydryl groups in permitting transformation and DNA binding of the glucocorticoid receptor.

, 1987
W Tienrungroj, Soheil Meshinchi, Edwin R. Sánchez, Sean E. Pratt, Joseph F. Grippo, Arne Holmgren, William B. Pratt   +6 more
openalex   +1 more source

Dexamethasone regulates gene expression in chondrocytes through MKP-1 and downregulates cholesterol hydroxylases CH25H and CYP7B1. [PDF]

Inflamm Res
Lehtola T, Pemmari A, Nummenmaa E, Valjus I, Hämäläinen M, Moilanen T, Vuolteenaho K, Moilanen E.   +7 more
europepmc   +1 more source

Abstract 135: A Phase 1 Study of Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment (LIGHT)

Ahmad A. Ballout, Daniel A. Tonetti
openalex   +1 more source

The preterm labor associated ADAMTS2 gene is induced by glucocorticoids

, 2018
Alasdair Jubb, Thomas P. Hofer, David Hume, Loems Ziegler‐Heitbrock   +3 more
openalex   +2 more sources

Efficacy of Telitacicept in Childhood‐Onset Systemic Lupus Erythematosus: A Prospective Multicenter Cohort Study With Inverse Probability of Treatment Weighting –Adjusted Comparison to a Historical Control Group Treated With Belimumab

Arthritis &Rheumatology, EarlyView.
Objective The therapeutic effects of telitacicept combined with standard of care (SoC) in childhood‐onset systemic lupus erythematosus (cSLE) remain unclear. This study aims to evaluate its efficacy in comparison with belimumab combined with SoC.
Chong Luo, Shu Su, Jingyue Liu, Junyu Lin, Jin Song, Zongwen Chen, Yuanyuan Peng, Lijun Jiang, Meng Jia, Li Wang, Xinhui Jiang, Wei Zhang, Zanhua Rong, Bo Zhao, Yajun Wang, Xuemei Tang   +15 more
wiley   +1 more source

Suprachiasmatic Nuclei Possess Glucocorticoid Receptors That Activate Downstream Signaling Pathways but Do Not Entrain Their Circadian Clock. [PDF]

Acta Physiol (Oxf)
Sládek M, Lužná V, Houdek P, Sumová A.   +3 more
europepmc   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

The role of glucocorticoids in recurrent idiopathic intussusception: a retrospective cohort study. [PDF]

BMC Pediatr
Zhang J, Liu T, Wang D, Li X, Wang L, Li S, Huang L, Shen Q.   +7 more
europepmc   +1 more source