Results 221 to 230 of about 443,164 (406)
The Effect of Glucose and of a Treatment by Glucocorticoids on the Inactivation in vitro of Liver Glycogen Phosphorylase [PDF]
, 1970 Willy Stalmans +3 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia +4 more
wiley +1 more source
Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 26-34, January 2023., 2023 ABSTRACT The combination of denosumab and teriparatide is an effective treatment strategy in postmenopausal osteoporosis, though skeletal gains are promptly lost when these agents are discontinued. In the DATA‐HD study, we reported that a single dose of zoledronic acid (ZOL) maintains the increases in areal spine and hip bone mineral density (BMD ...
Sabashini K. Ramchand +6 more
wiley +1 more source
Glucocorticoid-Induced Inhibition of T Cell Growth Factor Production [PDF]
, 1979 Steven Gillis +2 more
openalex +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan +3 more
wiley +1 more source
Liquid-chromatographic measurement of endogenous and exogenous glucocorticoids in plasma. [PDF]
, 1979 F J Frey, B M Frey, Leslie Z. Benet
openalex +1 more source
Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
INHIBITORY EFFECT OF ADRENAL GLUCOCORTICOIDS ON HISTAMINE RELEASE
, 1963 Hidemasa Yamasaki, Takashi Yamamoto
openalex +1 more source
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source