Results 171 to 180 of about 134,105 (265)

A Molecular-Dynamics-Guided Screening Pipeline Identifies Topical Glucocorticoid Receptor Modulators with Selective Epidermal Activation.

Skin Pharmacol Physiol
Tai FC, Lien HH, Lin SC, Hung YL, Cheng YP, Guo JW.   +5 more
europepmc   +1 more source

Bovine α-herpesvirus 1 replication and immediate early transcription unit 1 promoter are jointly stimulated by glucocorticoid receptor and DNA-dependent ATPases. [PDF]

J Gen Virol
El-Mayet FS, St Clair M, Costello B, Ostler JB, Jones C.   +4 more
europepmc   +1 more source

Incidence and Disease Course of Polymyalgia Rheumatica During Two Decades: A Nationwide Study Across Health Care Sectors in Denmark

Arthritis &Rheumatology, EarlyView.
Objective A new algorithm enables the identification of patients with polymyalgia rheumatica (PMR) across health care sectors in Denmark. We estimated annual incidence rates from 2003 to 2024 and described the disease course, including the occurrence of late‐onset giant cell arteritis (GCA) and prednisolone or prednisone (PDN) treatment.
Agnete Overgaard Donskov, Ellen Margrethe Hauge, Annette De Thurah, Mette Nørgaard, Kresten Krarup Keller   +4 more
wiley   +1 more source

Anti-Cancer Outcome of Glucocorticoid Receptor Transrepression by Synephrine Derivatives in Hematological Malignancies. [PDF]

Int J Mol Sci
Zhidkova EM, Savina ED, Migaleva DV, Vlasova OA, Valiev TT, Enikeev AD, Badun GA, Chernysheva MG, Dodonova SA, Kryukov AA, Kusov PA, Gordeev KV, Yurchenko EA, Matveev AV, Yakubovskaya MG, Lesovaya EA.   +15 more
europepmc   +1 more source

Shared and Distinguishing Features of Late‐Onset Rheumatic Diseases Fulfilling Polymyalgia Rheumatica Classification Criteria

Arthritis &Rheumatology, Accepted Article.
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Kerem Abacar, Ala Altaie, Andrew Barr, Sarah L. Mackie, Kulveer Mankia, Dennis McGonagle   +5 more
wiley   +1 more source

Impact of cumulative glucocorticoid exposure on vancomycin clearance in hospitalized children: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari, Ruud H. J. Verstegen, Cintia Cruz, Erin Chung, Aleena Azim, Shinya Ito, Tamorah R. Lewis   +6 more
wiley   +1 more source

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source

Context-dependent effect of glucocorticoid receptor activity shapes ovarian cancer cell plasticity and therapy response. [PDF]

Mol Cancer
De Girolamo M, Ibello E, Improda T, Tedesco I, Dell'Aversana C, Buonaiuto S, Arbucci S, D'Aniello C, De Cesare D, Franco R, Ambrosino C, Altucci L, Cobellis L, Patriarca EJ, Minchiotti G, Cobellis G.   +15 more
europepmc   +1 more source

The potential impact of H1 antihistamines on clinical outcomes in NSCLC patients undergoing EGFR‐TKIs treatment

British Journal of Clinical Pharmacology, EarlyView.
Background Epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR‐TKIs) have substantially improved outcomes in non‐small cell lung cancer (NSCLC); however, the development of treatment resistance remains a major clinical challenge. This study examines the association between concomitant prescriptions of H1‐antihistamines (H1AHs) and ...
Van Thuan Nguyen, Ngoc Hoang Le, Nhu Quynh Phan, Toan Trung Duong, Le Thi Anh Thu, Hsuan‐Chia Yang, Chih‐Wei Huang, Min‐Huei Hsu, Jason C. Hsu, Chien‐Tien Su, Phung‐Anh Nguyen   +10 more
wiley   +1 more source

Expression of Glucocorticoid Receptor and FOXO1/phospho-FOXO1 in Bladder Cancer as Independent Prognosticators. [PDF]

Cancer Genomics Proteomics
Ide H, Najafi MAE, Matsukawa T, Tatenuma T, Oya M, Miyamoto H.   +5 more
europepmc   +1 more source