Results 171 to 180 of about 142,613 (313)

The multimerization pathway of the glucocorticoid receptor. [PDF]

Nucleic Acids Res
Alegre-Martí A, Jiménez-Panizo A, Lafuente AL, Johnson TA, Montoya-Novoa I, Peralta-Moreno MN, Montanyà-Valluguera P, Ponsetí-Pons J, Abella M, Kim S, Díaz M, Vilaseca M, Pérez P, Fernández-Recio J, Rubio-Martínez J, Presman DM, Hager GL, Fuentes-Prior P, Estébanez-Perpiñá E.   +18 more
europepmc   +1 more source

Prescribing of Medication to Prevent Glucocorticoid Harms in Patients With Polymyalgia Rheumatica: A Cross‐Sectional Study and Two Emulated Target Trials in the Clinical Practice Research Datalink Aurum

Arthritis &Rheumatology, EarlyView.
Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig, David Jenkinson, James Bailey, Samantha Hider, Ian C. Scott, Sara Muller   +5 more
wiley   +1 more source

An AIB1 isoform rewires glucocorticoid receptor signaling to promote TNBC progression. [PDF]

iScience
Kiliti AJ, Sharif GM, McNamara ME, Rahhal R, Prewitt S, Schmidt MO, Wu C, Ma J, Glasgow E, Wellstein A, Riegel AT.   +10 more
europepmc   +1 more source

Glucocorticoid Receptor

Ensho, 1983
openaire   +2 more sources

Treatment of a Large Cohort of Childhood Chronic Noninfectious Uveitis in a Multicentric Large Study: Adalimumab Versus Methotrexate as First‐Line Therapy

Arthritis &Rheumatology, EarlyView.
Objective Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in juvenile idiopathic arthritis–associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheumatology and ophthalmology units at Florence, Italy ...
Ilaria Maccora, Catherine Guly, Cinzia de Libero, Giulia Carreras, Athimalaipet V. Ramanan, Gabriele Simonini   +5 more
wiley   +1 more source

Timing of Glucocorticoid Treatment Dictates Glucocorticoid Receptor Actions Modulating the NLRP3-Inflammasome Activation in Macrophages. [PDF]

FASEB J
Diaz-Jimenez D, Oakley RH, Hoffman JA, Bortner CD, Lih F, Li J, Williams JG, Scappini E, Gerrish KE, Garantziotis S, Archer TK, Cidlowski JA.   +11 more
europepmc   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

Targeting glucocorticoid receptor to enhance immunotherapy response in triple negative breast cancer. [PDF]

Breast Cancer Res
Yang L, Chen Z, Chen Y, Yang J, Liu S, Deng K, Xu J, Cui M, Fu Z.   +8 more
europepmc   +1 more source

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

Arthritis &Rheumatology, EarlyView.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun, Lingfang Xu, Haibing Chen, Mingshu Sun, Zhiqiang Li, Rui Li, Lidan Ma, Hui Zhang, Aichang Ji, Yuwei He, Na Wu, Le Yan, Robert Terkeltaub, Changgui Li   +13 more
wiley   +1 more source

Epigenetic regulation of the glucocorticoid receptor gene through methylation is linked to post-traumatic stress disorder. [PDF]

Sci Rep
Ye M, Lee HJ, Shim I.
europepmc   +1 more source