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Impact of glucocorticoid receptor polymorphism rs6198 on sepsis survival in a prospective multicenter cohort. [PDF]
Sombetzki C +12 more
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The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis. [PDF]
Durumutla HB +10 more
europepmc +1 more source
TENT5C functions as a corepressor in the ligand-bound glucocorticoid receptor and estrogen receptor α complexes. [PDF]
Li Y +5 more
europepmc +1 more source
Podocyte Glucocorticoid Receptor Expression and Treatment Outcome in Idiopathic Nephrotic Syndrome. [PDF]
van den Berge BT +4 more
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The human glucocorticoid receptor
2023Glucocorticoids are members of steroid hormones that are biosynthesized in the intermediate cellular zone of the adrenal cortex (zona fasciculata) and released into the peripheral blood as final products of the hypothalamic-pituitary-adrenal (HPA) axis, as well as under the control of the circadian biologic system.
Nicolas C, Nicolaides +1 more
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Glucocorticoid receptor blockers
Pituitary, 2022Mifepristone is the only glucocorticoid receptor antagonist currently approved for the treatment of Cushing's syndrome. Although originally developed as an abortifacient due to its blockade of the progesterone receptor, a number of case reports documented its efficacy as a glucocorticoid receptor blocker going back to 1985. The SEISMIC trial, published
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