Results 271 to 280 of about 2,425,230 (388)

Targeting glucocorticoid receptor signaling pathway for treatment of stress-related brain disorders. [PDF]

Pharmacol Rep
Göver T, Slezak M.
europepmc   +1 more source

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

iMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma, Hangyuan He, Kunpeng Wang, Juanjuan Guo, Liang Liu, Yuting Chen, Bin Li, Hao Xiao, Xufeng Li, Xiaoqian Lu, Tingting Wang, Yinxian Wen, Hui Wang, Liaobin Chen   +13 more
wiley   +1 more source

All-in-one CRISPR/Cas-engineered glucocorticoid-receptor knock-out EBV-gp350-CAR knock-in T cells are potent and resistant to dexamethasone. [PDF]

Exp Hematol Oncol
Kaeuferle T, Zwermann M, Stoll N, Ferrada-Ernst P, Jablonowski L, Zeidler R, Willier S, Stenger D, Yassin A, Stripecke R, Feuchtinger T.   +10 more
europepmc   +1 more source

Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2C134W Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors. [PDF]

Cancer Res
Welte T, Vuttaradhi VK, Khlebus EY, Brodsky A, Flores Legarreta A, Celestino J, Powell RT, Stephan CC, Nguyen N, Li J, Takamatsu S, Calzoncinth K, Sood AK, Gershenson DM, Futreal PA, Lawson B, Hillman RT.   +16 more
europepmc   +1 more source

Corticosterone and Mitochondrial Efficiency Are Associated With Changes in DNA Oxidative Damage During an Acute Stress Response in Leach's Storm‐Petrels (Hydrobates leucorhous)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner, Jack K. Dziubek, Nicole A. Joseph, Sarah E. Chapman, Tori J. Chace, Dongxiao Sun, Zachary T. Bitzer, Antoine Stier, Robert A. Mauck, Patricia L. Jones, Mark F. Haussmann   +10 more
wiley   +1 more source

Pharmacokinetics/pharmacodynamics of glucocorticoids: modeling the glucocorticoid receptor dynamics and dose/response of commonly prescribed glucocorticoids. [PDF]

ADMET DMPK
Levitt DG.
europepmc   +1 more source

Characterization and Quantification of Epidermal and Dermal Glucocorticoid Receptors in the Rat

, 1984
Kenneth T. Smith, Sam Shuster
openalex   +1 more source

Dexamethasone regime and clinical outcomes in children hospitalized with croup: A cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background High‐quality trial evidence supports the use of one dose of dexamethasone in the outpatient management of croup; however, there are no inpatient trials, and the optimal treatment regimen for the inpatient management of croup remains uncertain.
David D'Arienzo, Muhammadhasan Nasser, Peter J. Gill, Cornelia M. Borkhoff, Patricia C. Parkin, Sanjay Mahant   +5 more
wiley   +1 more source

The role of oxidative stress, glucocorticoid receptor and ARMC5 in lipid metabolism. [PDF]

Endocr J
Okuno Y, Fukuhara A, Shimomura I.
europepmc   +1 more source

Elevation in white blood cell count after corticosteroid use in noninfected hospitalized patients

Journal of Hospital Medicine, EarlyView.
Abstract Background It is widely accepted that corticosteroids cause leukocytosis. Clinicians must decide whether a rise in white blood cell (WBC) count is due to steroids versus other processes like developing infection. Objective The objective of this study is to measure the increase in white blood cell count after corticosteroid administration in ...
Erin Sullivan, Rebecca Schulte, Michael B. Rothberg   +2 more
wiley   +1 more source