Results 41 to 50 of about 164,711 (356)

Steroids, Pregnancy and Fetal Development

open access: yesFrontiers in Immunology, 2020
Maternal glucocorticoids critically rise during pregnancy reaching up to a 20-fold increase of mid-pregnancy concentrations. Concurrently, another steroid hormone, progesterone, increases.
Maria Emilia Solano, Petra Clara Arck
doaj   +1 more source

The glucocorticoid receptor in inflammatory processes : transrepression is not enough [PDF]

open access: yes, 2015
Glucocorticoids (GCs) are the most commonly used anti-inflammatory agents to treat inflammatory and immune diseases. However, steroid therapies are accompanied by severe side-effects during long-term treatment. The dogma that transrepression of genes, by
Dejager, Lien   +3 more
core   +2 more sources

Stress-induced enhancement of mouse amygdalar synaptic plasticity depends on glucocorticoid and ß-adrenergic activity. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Glucocorticoid hormones, in interaction with noradrenaline, enable the consolidation of emotionally arousing and stressful experiences in rodents and humans.
Ratna Angela Sarabdjitsingh   +4 more
doaj   +1 more source

Liver x receptors regulate the transcriptional activity of the glucocorticoid receptor: implications for the carbohydrate metabolism. [PDF]

open access: yesPLoS ONE, 2012
GLUCOCORTICOIDS are steroid hormones that strongly influence intermediary carbohydrate metabolism by increasing the transcription rate of glucose-6-phosphatase (G6Pase), a key enzyme of gluconeogenesis, and suppress the immune system through the ...
Nancy Nader   +5 more
doaj   +1 more source

A novel human glucocorticoid receptor SNP results in increased transactivation potential. [PDF]

open access: yes, 2017
Glucocorticoids are one of the most widely used therapeutics in the treatment of a variety of inflammatory disorders. However, it is known that there are variable patient responses to glucocorticoid treatment; there are responders and non-responders, or ...
Cho, Kiho   +5 more
core   +3 more sources

Concerted gene expression of hippocampal steroid receptors during spatial learning in male Wistar rats: a correlation analysis

open access: yesFrontiers in Behavioral Neuroscience, 2016
Adrenal and gonadal steroid receptor activities are significantly involved and interact in the regulation of learning, memory and stress. Thus, a coordinated expression of steroid receptor genes during a learning task can be expected.
Gert eLubec, Volker eKorz
doaj   +1 more source

The glucocorticoid receptor resource [PDF]

open access: yesNucleic Acids Research, 1996
The glucocorticoid receptor resource focuses on the structure-function relationships of the glucocorticoid receptor. As well as links to sequence and bibliographic databases via the World Wide Web, the database contains sequence comparisons of receptors from different species and source information for glucocorticoid receptor clones, probes, cell lines
M, Danielsen, E, Martinez
openaire   +2 more sources

Loss of FKBP5 Affects Neuron Synaptic Plasticity: An Electrophysiology Insight [PDF]

open access: yes, 2019
FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR.
Deng, Ran   +14 more
core   +1 more source

Melanocortin Regulation of Inflammation

open access: yesFrontiers in Endocrinology, 2019
Adrenocorticotropic hormone (ACTH), and α-, β-, and γ-melanocyte-stimulating hormones (α-, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin receptors), are components of an ancient modulatory system.
Wei Wang   +3 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

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