Results 161 to 170 of about 2,312,594 (289)

Impaired glucocorticoid receptor expression and mitochondrial metabolism in MDSCs contribute to glucocorticoid resistance in immune thrombocytopenia. [PDF]

Cell Mol Immunol, 2022
Kapur R.
europepmc   +1 more source

Effects of paraprobiotic Lactobacillus acidophilus LA‐5 on PANoptosis, oxidative stress and inflammation in acetic acid‐induced ulcerative colitis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Ulcerative colitis (UC) is a relapsing inflammatory bowel disease characterised by oxidative stress, inflammation and regulated cell death of the colonic mucosa. Because live probiotics may cause bacteraemia and sepsis in immunocompromised hosts, non‐viable (paraprobiotic) alternatives have attracted interest.
Adem Yavaş, Ezgi Özkıran, Ecem Akan
wiley   +1 more source

The role of AP-1 in glucocorticoid resistance in leukaemia

Glucocorticoids are used in the treatment of acute lymphoblastic leukaemia (ALL) and chronic lymphocytic leukaemia (CLL) but many patients develop glucocorticoid resistance on relapse. The ligand-activated glucocorticoid receptor inhibits activity of the
C. P. F., A. G., Pearson, Redfern, S., Hall, Bailey, A. D. J.   +7 more
core   +3 more sources

Beyond adrenal fatigue: reframing the adrenal stress index through neutrophil-mediated glucocorticoid resistance. [PDF]

Front Endocrinol (Lausanne)
Cardillo G.
europepmc   +1 more source

Drug Repurposing to Treat Glucocorticoid Resistance in Asthma. [PDF]

J Pers Med, 2021
Wang AL, Panganiban R, Qiu W, Kho AT, Chupp G, Meyers DA, Bleecker ER, Weiss ST, Lu Q, Tantisira KG.   +9 more
europepmc   +1 more source

Subcorneal Pustular Dermatosis, a Systematic Review and Pooled Analysis of a Rare and Underdiagnosed Disease

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Subcorneal pustular dermatosis (SPD), or Sneddon–Wilkinson disease, is a rare, relapsing pustular skin condition of unknown cause, characterised by subcorneal pustules. Objectives To summarise the demographic, clinical, histopathological, management and disease course of SPD.
Mason H. Crossman, Jeffrey Weng, Alysha Vuong, Lawrence Lin, Zhao Feng Liu, Christopher Y. Chew   +5 more
wiley   +1 more source

A preliminary study developing a scoring model incorporating fibrinogen-like protein 2 for predicting glucocorticoid resistance in thyroid eye disease. [PDF]

Thyroid Res
Matsuzawa K, Izawa S, Kadowaki K, Fukaya K, Matsumoto K, Nagata K, Okura T, Fujii S, Miyazaki D, Taniguchi SI, Yamamoto K, Imamura T.   +11 more
europepmc   +1 more source

Icariin Improves Glucocorticoid Resistance in a Murine Model of Asthma with Depression Associated with Enhancement of GR Expression and Function. [PDF]

Planta Med, 2023
Jin H, Zhou Y, Ye J, Qiu C, Jin W, Wang L.   +5 more
europepmc   +1 more source

Glucocorticoid Resistance [PDF]

, 2020
openaire   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source