Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Glucocorticoid resistance and hyperlactatemia: A tag team to worsen sepsis. [PDF]
Aziz M, Wang P.
europepmc +1 more source
ABSTRACT Introduction/Aims Current therapeutic management of juvenile myasthenia gravis (JMG) predominantly relies on conventional immunosuppressive therapies and expert consensus extrapolated from adult data, creating a critical gap in high‐quality, pediatric‐specific clinical evidence.
Jing Lin +14 more
wiley +1 more source
Primary Generalized Glucocorticoid Resistance and Hypersensitivity Syndromes: A 2021 Update. [PDF]
Nicolaides NC, Charmandari E.
europepmc +1 more source
Abstract Background In individuals with cystic fibrosis (CF), lean mass and muscle strength are important predictors of clinical outcomes. This study evaluated associations among body composition, handgrip strength, muscle quality, physical activity, and health‐related quality of life in CF. Methods This observational, cross‐sectional study included 27
Benjamin H. Crain +9 more
wiley +1 more source
Complete glucocorticoid resistance: a lethal disorder in the neonatal period. [PDF]
Segev N +5 more
europepmc +1 more source
Impaired glucocorticoid receptor expression and mitochondrial metabolism in MDSCs contribute to glucocorticoid resistance in immune thrombocytopenia. [PDF]
Kapur R.
europepmc +1 more source
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Beyond adrenal fatigue: reframing the adrenal stress index through neutrophil-mediated glucocorticoid resistance. [PDF]
Cardillo G.
europepmc +1 more source
Icariin Improves Glucocorticoid Resistance in a Murine Model of Asthma with Depression Associated with Enhancement of GR Expression and Function. [PDF]
Jin H +5 more
europepmc +1 more source

