Results 151 to 160 of about 291,048 (366)

Early Effects of Glucocorticoids on Nucleic Acid Metabolism of Rat Liver. [PDF]

open access: bronze, 1963
Kristian F. Jervell   +4 more
openalex   +1 more source

Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease

open access: yesAdvanced NanoBiomed Research, EarlyView.
Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang   +5 more
wiley   +1 more source

Mode of Action of Glucocorticoids

open access: hybrid, 1964
Paul D. Ray   +2 more
openalex   +1 more source

Expert Perspective: How, When, and Why to Potentially Stop Antiresorptive Drugs in Osteoporosis

open access: yesArthritis &Rheumatology, EarlyView.
Osteoporosis is a chronic disease, and antiresorptive treatments are often continued for many years. Despite their established efficacy in reducing fracture risk, the most commonly used antiresorptive treatments, bisphosphonates and denosumab, have short‐ and long‐term risks that, coupled with their benefits and other unique characteristics, influence ...
Giovanni Adami, Kenneth G. Saag
wiley   +1 more source

Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1:physiological regulator and pharmacological target for energy partitioning [PDF]

open access: yes, 2007
Alberts   +14 more
core   +1 more source

Time‐Dependent Effect of Prophylactic Trimethoprim‐Sulfamethoxazole on the Incidence of Serious Infections in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis: A Target Trial Emulation Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective The objective of this study was to investigate the effect of prophylactic trimethoprim‐sulfamethoxazole (TMP‐SMX) on the incidence of serious infections in patients with antineutrophil cytoplasmic antibody–associated vasculitis (AAV). Methods This multicenter cohort study was designed to emulate a target trial that studied 296 patients with ...
Yun Kyu Kim   +7 more
wiley   +1 more source

Overcoming reduced glucocorticoid sensitivity in airway disease:molecular mechanisms and therapeutic approaches [PDF]

open access: yes, 2010
Abraham   +150 more
core   +1 more source

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